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UnknownA novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma.
Not available
S-EPMC8163735 | biostudies-literature
UnknownBCL-XL is an actionable target for treatment of malignant pleural mesothelioma.
Not available
S-EPMC7603509 | biostudies-literature
UnknownPLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation.
Not available
S-EPMC5490236 | biostudies-literature
UnknownPotentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer.
Not available
S-EPMC9642964 | biostudies-literature
UnknownPhase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study.
Not available
S-EPMC5931084 | biostudies-literature
UnknownT cell factor 1 (TCF-1) defines T cell differentiation in colorectal cancer.
Not available
S-EPMC11401206 | biostudies-literature
UnknownMeta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration.
Not available
S-EPMC2495035 | biostudies-literature
UnknownBCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.
Not available
S-EPMC6482196 | biostudies-literature
UnknownVEGF-A, VEGFR1 and VEGFR2 single nucleotide polymorphisms and outcomes from the AGITG MAX trial of capecitabine, bevacizumab and mitomycin C in metastatic colorectal cancer.
Not available
S-EPMC8786898 | biostudies-literature
UnknownExperimental and spontaneous metastasis assays can result in divergence in clonal architecture.
Not available
S-EPMC10406815 | biostudies-literature
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