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TranscriptomicsLoss of the actin remodeler Eps8 causes calorie restriction and improved metabolic status in mice
In a variety of organisms, including mammals, caloric restriction improves metabolic status and lowers the incidence of chronic-degenerative diseases, ultimately leading to increased lifespan. Here we show that knockout mice for Eps8, a regulator of actin dynamics, display reduced bodyweight, partia...
ORGANISM(S): Mus musculus 
2010-03-09 | E-GEOD-14454 | biostudies-arrayexpress
UnknownBioinformatics and functional analysis of an Entamoeba histolytica mannosyltransferase necessary for parasite complement resistance and hepatical infection.
Not available
S-EPMC2239303 | biostudies-literature
ProteomicsHigh-throughput identification of functional regulatory SNPs in systemic lupus erythematosus
Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utilized SNP-seq and bioinformatic enrichment to interrogate 2180...
ORGANISM(S): Homo sapiens (Human) 
2024-08-02 | PXD048367 | Pride
Lc-msms Human B cell Sle 
UnknownSalivary dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus.
Not available
S-EPMC7192221 | biostudies-literature
UnknownPathologic findings at risk-reducing salpingo-oophorectomy: primary results from Gynecologic Oncology Group Trial GOG-0199.
Not available
S-EPMC4178524 | biostudies-literature
UnknownTranscranial Magnetic Stimulation for Long-Term Smoking Cessation: Preliminary Examination of Delay Discounting as a Therapeutic Target and the Effects of Intensity and Duration.
Not available
S-EPMC9300313 | biostudies-literature
TranscriptomicsRNA-seq expression profiling of humain MAIT cells in blood and liver as compared to mainstream TCD4+ and TCD8+ cells.
At variance with what is observed in mice, no distinct MAIT1 or MAIT17 subsets exist in human blood, as all MAIT cells express a variety of transcription factors such as Rorgt, Tbet, Eomes and Helios. However, they are also found in tissues in which they have specific effector functions. To determin...
ORGANISM(S): Homo sapiens 
2018-12-03 | E-MTAB-7143 | biostudies-arrayexpress
UnknownTrans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
Not available
S-EPMC6121630 | biostudies-literature
TranscriptomicsAtHB17 Regulates Photosynthetic Capacity
The transcriptional profiles of root quiescent center tissues from AtHB17 KO lines in Arabidopsis were compared to wild-type sibling lines. The transcriptional profiles of root quiescent center tissues from AtHB17 KO lines in Arabidopsis were compared to wild-type sibling lines.
ORGANISM(S): Arabidopsis thaliana 
2013-09-04 | E-GEOD-48127 | biostudies-arrayexpress
UnknownCombined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.
Not available
S-EPMC7892389 | biostudies-literature
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