Sort   by:  
 Page size 
ProteomicsQuantitative proteomics of small extracellular vesicles from lymphatic fluid for analyzing the premetastatic niche in melanoma
Melanoma is an aggressive form of skin cancer that often spreads via lymphatic pathways to regional and distant sites. Melanoma-derived lymphatic small extracellular vesicles (sEVs) play a crucial role in forming a tumor-supportive environment for metastasis, or premetastatic niche, within the first...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD063898 | Pride
ProteomicsHuman melanoma-derived extracellular vesicles reprogram dendritic cells potentially enabling lymph node metastases
Evolution of melanoma from a primary tumor to widespread metastasis is crucially dependent on lymphatic spread. The mechanisms regulating the initial step in metastatic dissemination via regional lymph nodes remain largely unknown. We have previously described a dysfunctional immune profile that pre...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD005539 | Pride
Metastasis4 Dendritic cells2 Lymphatics3 Extracellular vesicles1 Tumor immunology5 
UnknownBEAM: a randomized phase II study evaluating the activity of bevacizumab in combination with carboplatin plus paclitaxel in patients with previously untreated advanced melanoma.
Not available
S-EPMC4669379 | biostudies-literature
Sort   by:  
 Page size