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UnknownSREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.
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S-EPMC7611716 | biostudies-literature
TranscriptomicsSREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
Macrophages exhibit a spectrum of activation states ranging from classical to alternative activation1. Alternatively activated macrophages are involved in diverse pathophysiological processes such as confining tissue parasites2, improving insulin sensitivity3 or promoting an immune tolerant microenv...
ORGANISM(S): Mus musculus 
2021-07-30 | GSE179066 | GEO
ProteomicsHuman melanoma-derived extracellular vesicles reprogram dendritic cells potentially enabling lymph node metastases
Evolution of melanoma from a primary tumor to widespread metastasis is crucially dependent on lymphatic spread. The mechanisms regulating the initial step in metastatic dissemination via regional lymph nodes remain largely unknown. We have previously described a dysfunctional immune profile that pre...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD005539 | Pride
Metastasis4 Dendritic cells2 Lymphatics3 Extracellular vesicles1 Tumor immunology5 
ProteomicsNoninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis
Colorectal cancer is the 3rd commonly diagnosed cancer (10.2%) and 2nd cause of cancer death (9.2%) in all cancers.There will be estimated 1.8 million new colorectal cancer cases and 0.9 million colorectal cancer deaths in 20181. As the 5th incidence rates and mortality rates cancer in china, colore...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032291 |
GenomicsSREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
PRJNA742040 | ENA
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