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ProteomicsThrombin activation of the factor XI dimer is a multi-staged process for each subunit
Factor XI (FXI) is a protein in the intrinsic coagulation pathway that can be activated by two enzymes. In hemostasis, FXI is activated by thrombin, while FXIIa-mediated activation of FXI is thought to be prothrombotic. The interactions of these enzymes with FXI are poorly understood due to their tr...
ORGANISM(S): Homo sapiens (Human) 
2024-02-05 | PXD039489 | Pride
Molecular dynamics Factor xi Crosslinking mass spectrometry Phox Thrombin 
UnknownHydrogen-deuterium exchange mass spectrometry highlights conformational changes induced by factor XI activation and binding of factor IX to factor XIa.
Not available
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UnknownLife-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic.
Not available
S-EPMC9026249 | biostudies-literature
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