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GenomicsDiscovery of telomere repeat-binding factor in the malaria parasite Plasmodium falciparum
ChIP-seq experiments were performed for the putative telomere repeat-binding factor (PfTRF) in the malaria parasite Plasmodium falciparum strain 3D7. The gene encoding this factor (PF3D7_1209300) was endogenously tagged with either a GFP- or a 3xHA-tag and these transgenic parasite lines were used i...
ORGANISM(S): Plasmodium falciparum 
2016-07-15 | E-GEOD-76537 | biostudies-arrayexpress
ProteomicsMudPIT analyses of the chromatin associated proteins isolated from the nucleus of Plasmodium falciparum at three time-points of the intraerythrocytic development cycle
Parasite cultures- Plasmodium falciparum strain 3D7 was cultured in human O+ erythrocytes at 5% hematocrit. Cultures were synchronized at ring stage with 5% (w/v) D-sorbitol treatments. Parasite cultures (8% parasitemia in 5% hematocrit) were harvested 48 hours after the first sorbitol treatment (ri...
ORGANISM(S): Plasmodium Falciparum 3d7 (ncbitaxon:36329) 
2018-06-28 | MSV000082520 | MassIVE
TranscriptomicsTranscription profiling of T. brucei in vivo or in vitro samples, with in vitro samples either inclubated at 4oC or not to investiage the influence of culturing condtions on intracellular transport
The vast majority of molecular studies on T. brucei are carried out using in vitro cultures. Recently, whole-genome microarray analysis indicated significant differences between in vivo and in vitro cultures of the malaria parasite Plasmodium falciparum. Therefore, as an additional investigation int...
ORGANISM(S): Trypanosoma brucei 
2008-06-26 | E-MEXP-1540 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Aedes aegypti treated with permethrin to identify detoxification genes
Genomic analysis of detoxification genes in the mosquito Aedes aegypti.
ORGANISM(S): Aedes aegypti 
2008-02-09 | E-TABM-413 | biostudies-arrayexpress
TranscriptomicsThe impact of P53 loss on transcriptome changes following loss of Apc in the intestine
BACKGROUND: p53 is an important tumor suppressor with a known role in the later stages of colorectal cancer, but its relevance to the early stages of neoplastic initiation remains somewhat unclear. Although p53-dependent regulation of Wnt signalling activity is known to occur, the importance of thes...
ORGANISM(S): Mus musculus 
2015-06-25 | E-GEOD-70262 | biostudies-arrayexpress
TranscriptomicsDesign of a Diagnostic Pan-Pathogen Oligonucleotide Microarray including a sub-Array for Detection of Meningitis-Causing Bacterial Pathogens
Meningitis is a complex disease which can be caused by infection with either viral or bacterial pathogens. Viral meningitis is usually a sterile self-limiting disease with a good clinical prognosis, while bacterial meningitis is a potentially more serious disease with a higher mortality rate. Early ...
ORGANISM(S): Listeria monocytogenes 
2011-07-19 | E-GEOD-30794 | biostudies-arrayexpress
UnknownMultiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.
Not available
S-EPMC7615263 | biostudies-literature
TranscriptomicsAnalysis of Culex quinquefasciatus responses to WNV infection
Analysis of Culex quinquefasciatus responses to West Nile virus (WNV) infection at 7 and 14 days after ingestion of infected blood in the gut and carcass tissues. Comparison of WNV-infected to non-infected carcass and gut samples.
ORGANISM(S): Culex quinquefasciatus 
2011-11-01 | E-GEOD-23045 | biostudies-arrayexpress
TranscriptomicsAging reduces the pro-tumorigenic potential of bone marrow cells and influences triple-negative breast cancer progression
To examine the effects of recombinant granulin on human mammary stromal fibroblasts, we cultured immortalized GFP+ normal human mammary fibroblasts in the presence of recombinant human granulin (1ug/ml) or PBS every 24h for 6 days. To generate GRN-independent CAFs, we injected immortalized GFP+ huma...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-75333 | biostudies-arrayexpress
UnknownAltered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection.
Not available
S-EPMC8318295 | biostudies-literature
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