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ProteomicsA Siz1/Siz2-mediated SUMOylation programme inactivates the shugoshin-associated phosphatase-kinase network to stabilize sister kinetochore biorientation
The accurate segregation of chromosomes during mitosis relies on the attachment of sister chromatids to microtubules from opposite poles, called biorientation. Sister chromatid cohesion resists microtubule forces, generating tension which provides the signal that biorientation has occurred. How tens...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-03-25 | PXD019287 | Pride
Chromosome segregation Mitosis Shugoshin 
ProteomicsReductional meiosis I chromosome segregation is established by coordination of key meiotic kinases
Meiosis produces gametes through a specialised, two-step cell division, which is highly error-prone in humans. Reductional meiosis I, where maternal and paternal chromosomes (homologs) segregate, is followed by equational meiosis II, where sister chromatids separate. Uniquely during meiosis I, siste...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-13 | PXD012627 | Pride
Chromosome segregation Lc-ms Kinases Meiosis 
ProteomicsMudPIT analyses of the protein succination after fumarate treatment of whole cell extracts from Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) fumarate hydratase-deficient (FH-/-) cells
In brief, TCA-precipitated proteins from whole cell extracts treated with fumarate were urea-denatured, reduced, alkylated, and digested with endoproteinase LysC followed by trypsin. The peptide mixtures were loaded onto microcapillary fused silica columns (100um i.d.), packed with C18 reverse phase...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-03-13 | MSV000082160 | MassIVE
UnknownSecondary cell wall polysaccharides from Bacillus cereus strains G9241, 03BB87 and 03BB102 causing fatal pneumonia share similar glycosyl structures with the polysaccharides from Bacillus anthracis.
Not available
S-EPMC3110489 | biostudies-literature
TranscriptomicsBacillus cereus strain 31673
Comparative Genomic Hybridization. Analysis of genomic content of closely related Bacillus species. Refer to individual records for strain information. Refer to platform and individual sample records for experimental protocols.
ORGANISM(S): Bacillus anthracis str. Ames 
2010-06-05 | E-GEOD-568 | biostudies-arrayexpress
UnknownGenetic analysis of a rabies virus host shift event reveals within-host viral dynamics in a new host.
Not available
S-EPMC5729694 | biostudies-literature
UnknownIsogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits.
Not available
S-EPMC6235010 | biostudies-literature
UnknownInvestigation of an Imported Case of Rabies in a Juvenile Dog with Atypical Presentation.
Not available
S-EPMC4513475 | biostudies-literature
UnknownAntigenic and genetic characterization of a divergent African virus, Ikoma lyssavirus.
Not available
S-EPMC3983756 | biostudies-literature
UnknownConvergent genes shape budding yeast pericentromeres.
Not available
S-EPMC7279958 | biostudies-literature
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