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MetabolomicsTranscriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Carotenoids; UPLC-DAD assay)

BACKGROUND: Secondary metabolism contributes to the adaptation of a plant to its environment. In wine grapes, fruit secondary metabolism largely determines wine quality. Climate change is predicted to exacerbate drought events in several viticultural areas, potentially affecting ...

2021-08-16 | MTBLS889 | MetaboLights
MetabolomicsMulti-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Carotenoids; UPLC-DAD assay)

Grapes are one of the major fruit crops and they are cultivated in many dry environments. This study comprehensively characterizes the metabolic response of grape berries exposed to water deficit at different developmental stages. Increases of proline, branched-chain amino acids, phenylpropanoids...

2021-08-16 | MTBLS984 | MetaboLights
ProteomicsNanobody-mediated modulation of long RSH enzymes Rel and RelA catalysis by restriction of their conformational landscape
Long RSH enzymes, Rel and RelA, are the master regulators of (p)ppGpp alarmone levels in bacteria. Their catalytic activity is governed by transitions between a compact, hydrolysis-competent (HDON) state and an elongated, synthesis-competent (SYNTHON) state. The equilibrium between these states is m...
ORGANISM(S): Escherichia coli 
2026-04-28 | PXD067451 | Pride
Structural biology Rsh enzymes Nanobodies 
TranscriptomicsExpression data from breast cancer cell lines
Breast cancer is a genetically and phenotypically complex disease. To understand the role of microRNAs in this molecular complexity, we performed miRNA expression analysis in a cohort of molecularly well-characterized human breast cancer (BC) cell lines to discover miRNAs associated with the most co...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-41313 | biostudies-arrayexpress
MetabolomicsHigh-throughput carotenoid profiling using multivariate curve resolution (Stability of isoprenoids in grape extract)
We present automated data analysis of high throughput high-performance liquid chromatography with diode array detection (HPLC-DAD) data using multivariate curve resolution. This technique provides spectra and elution profiles of all UV-Vis active compounds present in the mixture. The specifics of us...
2014-07-01 | MTBLS85 | MetaboLights
UnknownSpecies catalogue of Drymaeus (Mesembrinus) Alberts, 1850 (Gastropoda: Bulimulidae) from Brazil and new data on morphology and distribution of Drymaeus (Mesembrinus) interpunctus (Martens, 1887).
Not available
S-EPMC10561649 | biostudies-literature
ProteomicsTargeted mass spectrometry of Tau preparations purified from Alzheimer’s Disease brains plus either the deubiquitylase USP21 or its activity-dead mutant C221A.
To characterise the abundance of ubiquitylated Tau peptides in the presence of active or inactive variants (wt 196-565 vs. C221A) of the broad spectrum deubiquitylase USP21. Tau peptides are obtained from Tau fibrils purified from post mortem human brains diagnosed with Alzheimer’s. Their detection ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-18 | PXD046645 | Pride
Alzheimer’s disease (de)ubiquitination/ubiquitylation Neurodegeneration 
UnknownConsolidation of Fir Wood by Poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) Treatment: Study of Surface and Mechanical Characteristics.
Not available
S-EPMC7284347 | biostudies-literature
UnknownMetabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties.
Not available
S-EPMC5249241 | biostudies-literature
MetabolomicsTranscriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Phenolics; UPLC-MS/MS assay)

BACKGROUND: Secondary metabolism contributes to the adaptation of a plant to its environment. In wine grapes, fruit secondary metabolism largely determines wine quality. Climate change is predicted to exacerbate drought events in several viticultural areas, potentially affecting ...

2019-04-07 | MTBLS897 | MetaboLights
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