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ProteomicsPRM and DDA Data for IR5 WIW and WIW Nanobodies
Journal Article: Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils
ORGANISM(S): Synthetic Antibodies Nanobodies 
2023-06-16 | MSV000092197 | MassIVE
ProteomicsSimultaneous selection of nanobodies for immune epitopes in the complex tumor microenvironment
In the rapidly advancing field of synthetic biology, there is a critical need for technology to discover targeting moieties for therapeutic biologics. We developed INSPIRE-seq, an approach that utilizes a nanobody library and next-generation sequencing to identify nanobodies selected for complex env...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD046363 | Pride
Phage Nanobodies Immune cells 
ProteomicsDevelopment of functional anti-Gn nanobodies specific for SFTSV based on next generation sequencing and proteomics
Severe fever with thrombocytopenia syndrome (SFTS) is an acute infectious disease caused by novel bunyavirus (SFTSV), with a mortality rate of 6.3% ~ 30%. To date, there is no specific treatment for SFTS. Previously, our studies demonstrate that SFTSV surface glycoprotein (Glycoprotein N, Gn) is a p...
ORGANISM(S): Camelidae 
2024-01-26 | PXD032731 | Pride
Lc ms/ms Nanobody Camel 
GenomicsPfs48/45 nanobodies block Plasmodium falciparum transmission
Pfs48/45 nanobodies
PRJEB88774 | ENA
GenomicsSelection of Novel Nanobodies Targeting EGFR
Selection of Novel Nanobodies Targeting EGFR Using Phage Display Library
PRJEB35883 | ENA
ProteomicsAnalysis of conformational changes induced by binding of allosteric nanobodies to a bacterial LRRK2 homologue by CX-MS
As part of an in-depth characterization of nanobodies directed against the Chlorobium tepidum protein CtRoco, a bacterial LRRK2 homologue, chemical crosslinking combined with mass spectrometry (CX-MS) was performed. Two allosteric nanobodies binding to two different epitopes in the LRR and the Roc d...
ORGANISM(S): Chlorobium tepidum 
2024-04-23 | PXD046634 | Pride
Lrrk2 Dsso Nanobodies Crosslinking Ctroco 
GenomicsE. coli Nanobodies
Rapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies
PRJEB78364 | ENA
GenomicsGeneration of synthetic Acinetobacter baumannii specific nanobodies
Generation of synthetic Acinetobacter baumannii specific nanobodies
PRJNA837907 | ENA
GenomicsS2 nanobodies
Mutational resistance of SARS-CoV-2 specific nanobodies against S2 domain
PRJEB104690 | ENA
ProteomicsAn HDX-MS optimised approach to characterise nanobodies as tools for biochemical and structural studies
Given the far-reaching applications of nanobodies, a stream-lined approach to characterizing nanobodies tailored to its intended application is warranted. Camelids can produce a large number of antibodies that can bind to a host of epitopes spanning the entire protein of interest, making identificat...
ORGANISM(S): Homo sapiens (Human) 
2021-09-22 | PXD025207 | Pride
Hdx-ms Pi3k Nanobody 
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