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The basic biology of bacteriophage–host interactions has attracted increasing attention due to a renewed interest in the therapeutic potential of bacteriophages. In addition, knowledge of the host pathways inhibited by phage may provide clues to novel drug targets. However, the effect of phage on ba...
2018-05-03 | MTBLS431 | MetaboLights
Widespread in bacteria and archaea, Toxin-antitoxin (TA) systems have been recently demonstrated to function in phage defense. Here we characterize the anti-phage function of a type IV TA system, ShosTA. Using structural and biochemical approaches, we show that ShosT couples phosphoribosyltransferas...
2025-02-17 | MTBLS11212 | MetaboLights

Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly linked to gut microbial dysbiosis. To date, most studies have been limited to bacterial taxa, neglecting viruses and fungi, and their interactions. Here we performed shotgun metagenomic and ITS2 sequencing on fecal s...

2026-03-18 | MTBLS14073 | MetaboLights
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ORGANISM(S): Gallus gallus 
Identification of Serratia phage JS26 structural proteins through LC-MS/MS
ORGANISM(S): Viruses Serratia phage JS26 
2021-12-03 | PXD029878 | Pride
Phages are viruses that specifically infect and kill bacteria. Bacterial fermentation and biotechnology industries see them as enemies, however, they are also investigated for the treatment or prevention of infections caused by multidrug resistant bacteria. Whether foes or allies, their importance i...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 Lactococcus phage 
2019-01-29 | PXD011263 | Pride
E. faecalis OG1RF cultures were infected with lytic phage VPE25 and proteomic profile of infected cells were compared to uninfected E. faecalis cells using 1D-LC-MS/MS analyses.
ORGANISM(S): Enterococcus phage VPE25 Enterococcus faecalis OG1RF 
2024-07-27 | PXD026873 | Pride
Staphylococcus phage 812, strain K1/420, is a broad-acting bacteriophage infecting S. aureus. Phage 812 belongs to the family Herelleviridae and is closely related to kayviruses. We conducted a structural study of the viral particle of phage 812 before and after genome ejection. We characterized the...
ORGANISM(S): Staphylococcus phage 812K1/420 Staphylococcus aureus 
2026-01-19 | PXD071586 | Pride
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