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GenomicsChromatin accessibility, p300 and histone acetylation define PML-RARalpha- and AML1-ETO-binding sites
Chromatin accessibility is a key determinant of cell-type-specific gene expression. Here, we have investigated the chromatin architecture of different acute myeloid leukemia (AML) cells and the changes in accessibility when NB4 (APL) cells undergo the process of differentiation. For nuclease-accessi...
ORGANISM(S): Homo sapiens 
2012-08-29 | E-GEOD-30254 | biostudies-arrayexpress
ProteomicsProteomes of E. coli W3110 samples grown in different growth media
This dataset contains E. coli W3110 samples grown in different growth conditions and harvested at different growth stages. A mapping between conditions and files is contained in the SDRF. This dataset is one of 40 projects included in the E. coli PanProteome PeptideAtlas build:Escherichia coli is a ...
ORGANISM(S): Escherichia coli 
2025-09-18 | PXD058808 | Pride
Growth medium Growth phase E.coli Lc-ms/ms 
TranscriptomicsExpression data from breast cancer cell lines
Breast cancer is a genetically and phenotypically complex disease. To understand the role of microRNAs in this molecular complexity, we performed miRNA expression analysis in a cohort of molecularly well-characterized human breast cancer (BC) cell lines to discover miRNAs associated with the most co...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-41313 | biostudies-arrayexpress
ProteomicsProteomics of E. coli extracellular vesicles
Escherichia coli A0 34/86 (EcO83) is a probiotic bacterium that is used in newborns to prevent nosocomial infections and diarrhoea. Mechanistically, EcO83 enhances innate immunity by inducing key inflammatory cytokines in vitro, and when administered intranasally, it modulates the recruitment of cel...
ORGANISM(S): Escherichia coli 
2025-05-07 | PXD052178 | Pride
Extracellular vesicles E. coli Eco83 Proteome 
MetabolomicsMulti-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Carotenoids; UPLC-DAD assay)

Grapes are one of the major fruit crops and they are cultivated in many dry environments. This study comprehensively characterizes the metabolic response of grape berries exposed to water deficit at different developmental stages. Increases of proline, branched-chain amino acids, phenylpropanoids...

2021-08-16 | MTBLS984 | MetaboLights
MetabolomicsTranscriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Carotenoids; UPLC-DAD assay)

BACKGROUND: Secondary metabolism contributes to the adaptation of a plant to its environment. In wine grapes, fruit secondary metabolism largely determines wine quality. Climate change is predicted to exacerbate drought events in several viticultural areas, potentially affecting ...

2021-08-16 | MTBLS889 | MetaboLights
UnknownPostrelease movement and habitat selection of translocated pine martens Martes martes.
Not available
S-EPMC7297779 | biostudies-literature
ProteomicsNanobody-mediated modulation of long RSH enzymes Rel and RelA catalysis by restriction of their conformational landscape
Long RSH enzymes, Rel and RelA, are the master regulators of (p)ppGpp alarmone levels in bacteria. Their catalytic activity is governed by transitions between a compact, hydrolysis-competent (HDON) state and an elongated, synthesis-competent (SYNTHON) state. The equilibrium between these states is m...
ORGANISM(S): Escherichia coli 
2026-04-28 | PXD067451 | Pride
Structural biology Rsh enzymes Nanobodies 
UnknownMultiple system atrophy and apolipoprotein E.
Not available
S-EPMC5889322 | biostudies-literature
UnknownE-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer.
Not available
S-EPMC6193986 | biostudies-literature
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