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Aims: establishment of reference samples to investigate gene expression selective for endocrine or ductal-exocrine cells within the adult human pancreas. To this end, human islet endocrine cells, FACS-enriched in insulin+ cells, (n=3) and human exocrine ductal cells (n=2) are compared on Affymetrix ...
ORGANISM(S): Homo sapiens 
Quantitative proteomics of rat and human pancreatic beta cells
ORGANISM(S): Rattus norvegicus (Rat) 
2015-08-04 | PXD001816 | Pride
Outline: using label-free alternate-scanning LC-MS/MS, we compared the proteomic architecture of core functional pathways in pancreatic beta cells of human origin. Results: we quantified the relative molar abundance of 707 proteins mainly composed of functional pathways of metabolism, protein synthe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082882 | MassIVE
CD8 ⁺ T cells can rapidly produce effector molecules following activation. This activation triggers fast changes in gene expression that rely on control of mRNA levels via multiple transcriptional and post-transcriptional mechanisms, including RNA modifications. N ⁶ -methyladenosine (m ⁶ A) is an ab...
ORGANISM(S): Homo sapiens (Human) 
2025-11-24 | PXD059083 | Pride
Neonatal beta cells are considered developmentally immature and hence less glucose-responsive. To study the acquisition of mature glucose-responsiveness, we compared glucose-regulated redox state, insulin synthesis and secretion of beta cells purified from neonatal or 10-weeks old rats to their tran...
ORGANISM(S): Rattus norvegicus (Rat) 
2014-12-12 | PXD001577 | Pride
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