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MetabolomicsA data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity
The mechanisms responsible for weight loss-induced improvement in insulin sensitivity are partially understood. Greater insight can now be achieved through deep phenotyping and data integration. Here, we used an integrative approach to investigate associations between changes in insulin sensitivity ...
2021-02-11 | MTBLS653 | MetaboLights
MetabolomicsRapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats
INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of...
2020-06-11 | MTBLS804 | MetaboLights
TranscriptomicsA predictive and prognostic 38-gene expression signature for metastatic relapse in breast cancer
Background Currently, no gene-expression signature (GES) established from node-positive cohorts, able to predict breast cancer evolution after systemic adjuvant chemotherapy, exists. Methods Gene-expression profiles of 252 node-positive patients (median follow-up: 7.7 years), mostly included in a ra...
ORGANISM(S): Homo sapiens 
2008-11-27 | E-GEOD-11264 | biostudies-arrayexpress
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
ModelsFink2008_VentricularActionPotential
This a model from the article: Contributions of HERG K+ current to repolarization of the human ventricular action potential. Fink M, Noble D, Virag L, Varro A, Giles WR. Prog Biophys Mol Biol 2008 Jan-Apr;96(1-3):357-76 17919688 , ...
2005-01-01 | MODEL1006230009 | BioModels
TranscriptomicsStromal factors SDF1alpha, sFRP1 and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells
The identified stromal factors SDF1alpha, sFRP1 and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells. Human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons are potentially useful for treating Parkinson’s disease (PD) through cell replacement therapy. Gen...
ORGANISM(S): Mus musculus 
2012-06-24 | E-GEOD-20503 | biostudies-arrayexpress
UnknownVariation in leaf wettability traits along a tropical montane elevation gradient.
Not available
S-EPMC5412938 | biostudies-literature
UnknownContinuing a search for a diagnosis: the impact of adolescence and family dynamics.
Not available
S-EPMC9830697 | biostudies-literature
TranscriptomicsIGR_PhilippeVielh_THY_CGH
Although fine needle aspiration (FNA) cytology is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains challenging in follicular neoplasms. Identification of genomic alterations in cytological specimens that distinguish between benign and malignant follicu...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-MTAB-1575 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis reveals importance of thermal effect in cellular response to millimeter wave exposure
To evaluate the effect of millimeter waves (MMW) exposure on the gene expression, we have employed whole genome microarray expression profiling. Neonatal primary Keratinocyte cells pooled from 3 healthy donors were exposed ex vivo, 3 hours at 20 mW/cm². At this condition, corresponding to the maxim...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-57135 | biostudies-arrayexpress
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