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TranscriptomicsChromatin immunoprecipitation to identify H-NS and RNA polymerase (beta-subunit) binding sites on the Salmonella typhimurium chromosome
Chromatin immunoprecipitation experiment to identify H-NS and RNA polymerase (beta-subunit) binding sites on the Salmonella Typhimurium chromosome
ORGANISM(S): Salmonella typhimurium 
2006-08-17 | E-MEXP-806 | biostudies-arrayexpress
TranscriptomicsTelomere behavior in a hybrid yeast
Telomeres and the protein/RNA complexes involved in maintaining them are rapidly evolving systems across eukaryotes. Using two Saccharomyces species, S. cerevisiae and S. bayanus, we provide evidence that the telomere systems of these two closely related yeasts have evolved significantly apart and t...
ORGANISM(S): Saccharomyces bayanus 
2010-05-19 | E-GEOD-15877 | biostudies-arrayexpress
TranscriptomicsEstrogens and selective estrogen receptor modulators regulate gene and protein expression in the mesenteric arteries
Estrogen is a reproductive steroid hormone that has both beneficial and detrimental effects on the cardiovascular system. Selective estrogen receptor modulators (SERMs) exhibit partial estrogen agonist/antagonist activity in estrogen target tissues. Since we still have an incomplete picture of the ...
ORGANISM(S): Rattus norvegicus 
2011-07-06 | E-GEOD-23037 | biostudies-arrayexpress
UnknownSpecific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines-an exploratory sub-study of the BRACE trial.
Not available
S-EPMC11058726 | biostudies-literature
UnknownMutagenesis on a complex mouse genetic background by site-specific nucleases.
Not available
S-EPMC11588839 | biostudies-literature
GenomicsEGAS00001000262-sc-20140722 - samples
To characterize the subclonal genomic architecture of androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of 51 tumours from 10 patients to an average sequencing depth of 55x, including multiple metastases from different anatomic sites in each patient and, in fiv...
EGAD00001000891 | EGA
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
UnknownInsulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.
Not available
S-EPMC11068109 | biostudies-literature
UnknownTrans-lesional fractional flow reserve gradient as derived from coronary CT improves patient management: ADVANCE registry.
Not available
S-EPMC9719736 | biostudies-literature
TranscriptomicsTranscriptomic analysis of human cybrid cell lines harboring increasing levels of the mitochondrial DNA (mtDNA) 3243A>G mutation
Mitochondria generate signals of adaptation that regulate nuclear genes expression via retrograde signaling. But this phenomenon is complexified when qualitatively different mitochondria and mitochondrial DNA (mtDNA) coexist within cells. Although this cellular state of heteroplasmy leads to diver...
ORGANISM(S): Homo sapiens 
2014-09-02 | E-GEOD-56158 | biostudies-arrayexpress
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