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During cell division, transcription factors (TFs) are removed from chromatin twice, during DNA synthesis, and during condensation of chromosomes. How TFs can efficiently find their sites following these stages has been unclear. Here, we have analyzed the binding pattern of expressed TFs in human col...
ORGANISM(S): Homo sapiens 
Differential gene expression in M. tuberculosis and M. africanum patients under TB treatment Gene expression analysis of whole blood RNA from tuberculosis patients prior to and following treatment
ORGANISM(S): Homo sapiens 
TGF-beta1 is the major cytokine driver of fibrotic scarring observed in diabetic nephropathy and other fibrosis-related diseases. RNA-sequencing offers the potential for more sensitive assessment of the TGF-M-CM-^_1-driven transcriptome. There were two treatment groups: vehicle, 48 hr TGFb1. Each tr...
ORGANISM(S): Homo sapiens 
MATERIALS AND METHODS: The genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast cancer, we set up an ex vivo coculture model with human benign and malignant breast epithelial cells with endothelial cells to determine the asso...
ORGANISM(S): Homo sapiens 
The extensively studied intracellular pathogen, L. monocytogenes, is an ideal model for identifying small-molecule agents for treating bacterial infections. By selecting specific biological targets in L. monocytogenes, which are common to Gram-positive pathogens, we could extrapolate drug discovery ...
ORGANISM(S): Listeria monocytogenes 10403S 

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
There is a current need to monitor human exposure to a large number of pesticides and other chemicals of emerging concern (CECs). This requires screening analysis with high confidence for these compounds and their metabolites in complex matrices, which is hampered by the fact that no reference stand...
2022-01-17 | MTBLS2402 | MetaboLights
Comparison of D. shibae wild-type with single gene knock-out strains of a phosphorelay conserved in Alphaproteobacteria (M-bM-^HM-^FctrA, M-bM-^HM-^FchpT and M-bM-^HM-^FcckA) Loop-design, two biological replicates of D. shibae wild-type, M-bM-^HM-^FctrA, M-bM-^HM-^FchpT and M-bM-^HM-^FcckA in mid-ex...
ORGANISM(S): Dinoroseobacter shibae DFL 12 
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