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GenomicsGenome-wide map of Gata6 DNA binding in mouse pancreas
We have previously described in mouse models that pancreas-specific deletion of Gata6 results in pancreas alterations by rendering pancreatic acinar cells in a non-fully differentiation state, and furthermore it accelerates tumor initiation and progression in a pro-tumorigenic context (KrasG12V exp...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-57090 | biostudies-arrayexpress
UnknownSynergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis.
Not available
S-EPMC3870512 | biostudies-literature
GenomicsChIP-seq experiments of Estrogen Receptor Alpha (ERa) in the human breast cancer cell line T47D stably expressing GFP or neoGATA3
In this study, we investigated the functions of the most common GATA3 mutation (X308_Splice) that we called “neoGATA3”. Analysis of available molecular data from >3000 breast cancer patients revealed a dysregulation of the ERa-dependent transcriptional response in tumors carrying this mutations. ChI...
ORGANISM(S): Homo sapiens 
2020-06-29 | E-MTAB-9121 | biostudies-arrayexpress
TranscriptomicsGene expression profile in DRG neurons over-expressing NRG1 type III intracellular domain
In DRG neurons NRG1 type III intacellular domain (ICD) moves to the nucleus upon contact with Schwann cells. We aimed to investigate genes up/down regulated by ICD. We analyzed total RNA from DRG neurons over-expressing ICD comparing it to RNA from wild-type DRG neurons and RNA from DRG neurons over...
ORGANISM(S): Rattus norvegicus 
2014-09-26 | E-GEOD-61784 | biostudies-arrayexpress
UnknownGain of Function of Malate Dehydrogenase 2 and Familial Hyperglycemia.
Not available
S-EPMC8852227 | biostudies-literature
UnknownAmiodarone or Implantable Cardioverter-Defibrillator in Chagas Cardiomyopathy: The CHAGASICS Randomized Clinical Trial.
Not available
S-EPMC11447631 | biostudies-literature
UnknownRisk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
Not available
S-EPMC6306365 | biostudies-literature
UnknownAssociation of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes.
Not available
S-EPMC6280443 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
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