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ProteomicsSARS-CoV-2 Infection Impacts Glutamate/Glutamine Metabolism in Syrian Hamster Central Nervous System
Coronaviruses belong to a well-known family of enveloped RNA viruses and the causative agent of the common cold. Although the seasonal coronaviruses do not pose a threat to human life, three members of this family, i.e., SARS-CoV, MERS-CoV and recently, SARS-CoV2, may cause severe acute respiratory ...
ORGANISM(S): Mesocricetus auratus (Golden hamster) 
2022-09-28 | PXD029426 | Pride
Sars-cov2 Proteomics Glutamine Neuropathology Covid-19 
UnknownMortality, hospitalizations, and persistence of symptoms in the outpatient setting of the first COVID-19 wave in Brazil: results of SARS-Brazil cohort study.

Objective

To evaluate deaths, hospitalizations, and persistence of symptoms in patients with COVID-19 after infection in an outpatient setting during the first COVID-19 wave in Brazil.

Methods

This prospective cohort was between April 2020 and February 2021. Hospitalized or non-hospit...
S-EPMC11323834 | biostudies-literature
UnknownABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores.

Objectives

The majority of available scores to assess mortality risk of coronavirus disease 2019 (COVID-19) patients in the emergency department have high risk of bias. Therefore, this cohort aimed to develop and validate a score at hospital admission for predicting in-hospital mortality in ...
S-EPMC8302820 | biostudies-literature
UnknownSmall Myristoylated Protein-3, Identified as a Potential Virulence Factor in Leishmania amazonensis, Proves to be a Protective Antigen against Visceral Leishmaniasis.
In a proteomics approach conducted with Leishmania amazonensis, parasite proteins showed either an increase or a decrease in their expression content during extensive in vitro cultivation, and were related to the survival and the infectivity of the parasites, respectively. In the current study, a co...
S-EPMC5796078 | biostudies-literature
UnknownThe NICHD International Site Development Initiative perinatal cohorts (2002-09).
Not available
S-EPMC3396326 | biostudies-literature
UnknownAnemia Acuity Effect on Transfusion Strategies in Acute Myocardial Infarction: A Secondary Analysis of the MINT Trial.

Importance

In patients with acute myocardial infarction (MI), limited physiologic adaptation to acute anemia might lead to greater benefit from a liberal red blood cell (RBC) transfusion strategy. Data on such a possible benefit are lacking.

Objectives

To compare acute anemia with chr...
S-EPMC11530937 | biostudies-literature
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.

Background

Thrombosis and inflammation may contribute to the risk of death and complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation may improve outcomes in noncritically ill patients who are hospitalized with Covid-19.
S-EPMC8362594 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown1 to be highly efficient for discovery of genetic associations2. Despite the advanced stage of illness at presentation, we have shown that host genetics in patie...
S-EPMC10208981 | biostudies-literature
UnknownArthroplasty-CervicalP001 - Double Crush Syndrome of the Vertebral Artery Loop and Foraminal Stenosis Causing Monoparesis
Not available
S-EPMC5724662 | biostudies-literature
UnknownNew-onset atrial fibrillation and chronic coronary syndrome in the CLARIFY registry.

Background and aims

Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study aims to describe the incidence, predictors, and impact on cardiovascular (CV) outcomes of NOAF in CCS patients.

Methods

Data from the international...
S-EPMC10834159 | biostudies-literature
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