Sort   by:  
 Page size 
TranscriptomicsAURATUS goldfish environmental genomics projects: dopamine depletion in hypothalamus and telencephalon
Sexually mature (mid-May) adult female goldfish received a single injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP; 50 ug/g body weight at 5 uL/g body weight) or 0.6% saline on day 0 and a single injection of alpha-methyl-p-tyrosine (aMPT; 240 ug/g body weight at 5 uL/g body weight) ...
ORGANISM(S): Carassius auratus 
2013-03-20 | E-GEOD-16044 | biostudies-arrayexpress
TranscriptomicsAuratus goldfish genome project: effects of fluoxetine on female goldfish
A goldfish brain enriched cDNA combined with a carp microarray (Gracey et al., 2004). Female adult goldish were treated twice a week for 17 days, for a total of five injections. Each of the injections consisted of 5 μg fluoxetine/g of body weight with an injection volume of 1μl/g. The telencepha...
ORGANISM(S): Carassius auratus 
2010-07-01 | E-GEOD-5420 | biostudies-arrayexpress
TranscriptomicsAURATUS goldfish environmental genomics projects: SKF 38393 in the telencephalon
Sexually mature female goldfish were administered 2 i.p. injections: 1) 0.1% DMSO in 0.6% saline or SKF 38393 (40 µg/g) dissolved in 0.1% DMSO in 0.6% saline, and; 2) 0.6% saline. A common reference design was used: 4 independent groups of telencephali from sexually mature female goldfish treated wi...
ORGANISM(S): Carassius auratus 
2013-03-20 | E-GEOD-14608 | biostudies-arrayexpress
TranscriptomicsAURATUS goldfish environmental genomics projects: quinpirole in the telencephalon
Sexually mature female goldfish were administered 2 i.p. injections: 1) 0.1% DMSO in 0.6% saline, and; 2) 0.6% saline OR quinpirole (2 ug/g) dissolved in 0.6% saline. A common reference design was used: 4 independent groups of telencephali from sexually mature female goldfish treated with 2 ug/g qui...
ORGANISM(S): Carassius auratus 
2013-03-20 | E-GEOD-14609 | biostudies-arrayexpress
TranscriptomicsAURATUS goldfish environmental genomics projects: SKF 38393 in the hypothalamus
Sexually mature female goldfish were administered 2 i.p. injections: 1) 0.1% DMSO in 0.6% saline or SKF 38393 (40 µg/g) dissolved in 0.1% DMSO in 0.6% saline, and; 2) 0.6% saline. A common reference design was used: 4 independent groups of hypothalami from sexually mature female goldfish treated w...
ORGANISM(S): Carassius auratus 
2011-08-21 | E-GEOD-14607 | biostudies-arrayexpress
TranscriptomicsAURATUS goldfish environmental genomics projects: fadrozole in the telencephalon
Sexually mature female goldfish were exposed (waterborne) to 50 ug/L fadrozole or untreated water (control) to examine the global gene expression of fadrozole on the telencephalon. A common reference design was used: 5 independent groups of telencephalonic tissue from sexually mature female goldfish...
ORGANISM(S): Carassius auratus 
2010-05-16 | E-GEOD-14558 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxin and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. We investigated the gene expression profile in ...
ORGANISM(S): Danio rerio 
2010-09-30 | E-GEOD-22662 | biostudies-arrayexpress
TranscriptomicsInterlab microarray comparison Lab C
Microarrays are used to assess the impacts of aquatic contaminants in both laboratory and field studies, which necessitates the validation of the comparability of microarray data generated by different laboratories before this tool is adopted for regulatory toxicology or environmental monitoring. F...
ORGANISM(S): Pimephales promelas 
2016-05-31 | E-GEOD-81348 | biostudies-arrayexpress
TranscriptomicsThe transcriptomic response to finasteride in the Silurana tropicalis testis
An ex vivo protocol was optimized to expose testis tissues from juvenile Silurana tropicalis to 5 uM finasteride. Testis tissues were incubated in L-15 media with (n = 8) and without (n = 8) finasteride for 6 h at 26 °C on top of an orbital shaker. Afterwards, the tissues were flash frozen on dry i...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2014-04-01 | E-GEOD-46366 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles in rat hair follicles after single wave blasting impact
Male Sprague-Dawley (SD) rats (350 - 400 g) were anaesthetized with 3% isoflurane for 3 min in a closed induction chamber. A helium driven shock tube was used at various shock wave pressures (20 - 30 psi). The exposure system has been developed so that the animals are exposed head only to a ?prima...
ORGANISM(S): Rattus rattus 
2014-04-01 | E-GEOD-46367 | biostudies-arrayexpress
Sort   by:  
 Page size