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TranscriptomicsGene expression analysis of relapse and no-relapse Wilms tumor
Wilms tumor (WT), the commonest renal tumor of the childhood, is originated from pluripotent metanephric blastemal cells resulting in tumors with triphasic histology, composed by blastemal, epithelial, and stromal cells. Histological subtype and tumor stage have long been recognized as important pro...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-22696 | biostudies-arrayexpress
TranscriptomicsTransduction signaling signature of Wilms tumor revealed by parallel analysis of kidney differentiation
Precise regulation of transduction signaling pathways genes is crucial for correct differentiation of kidney cells and perturbation may lead to tumor onset. Wilms tumors (WT), or nephroblastoma, originates from the metanephric blastema cells, which were unable to complete the differentiation, result...
ORGANISM(S): Mus musculus 
2011-12-07 | E-GEOD-25965 | biostudies-arrayexpress
TranscriptomicsCo-expression network analysis from genes involved with neural-differentiation shows specific pattern in patients with schizophrenia
Schizophrenia is a severe and debilitating neuropsychiatric disorder with the involvement of genetic and environmental factors contributing to its pathogenesis. The specific role of the brain cell types in the disease remains uncovered due to the difficulties in accessing diseased tissue. This study...
ORGANISM(S): Homo sapiens 
2014-10-09 | E-GEOD-62105 | biostudies-arrayexpress
TranscriptomicsMethylome analysis of normal kidney, nephrogenic rest and Wilms tumor
Genome wide DNA methylation profiling of normal kidney (n=36), nephrogenic rest (n=22) and Wilms tumour (n=37) was performed using the Illumina 450k array. Two papers were composed after analysis of this data (1) describes comparative analysis of 22 matched normal kidney-Wilms tumour pairs which ide...
ORGANISM(S): Homo sapiens 
2014-07-08 | E-GEOD-59157 | biostudies-arrayexpress
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