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TranscriptomicsTranscript analyses of cisplatin and Sky1 effects in Saccharomyces cerevisiae
Sky1 is a Saccharomyces cerevisiae rich serine-arginine (SR) protein-specific kinase and its enzymatic activity is essential in the cytotoxicity caused by cisplatin, although the molecular mechanisms supporting this function are not understood. We present a transcriptome analysis discriminating betw...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-41094 | biostudies-arrayexpress
TranscriptomicsTarget mRNAs induce tailing and trimming of Ago2-loaded miRNAs in neurons
We show that target mRNAs trigger the non-templated addition of nucleotides (mainly adenosines and uridines) and shortening of their cognate miRNAs in primary hippocampal neurons. The induced effect is observable both in total RNA and in Ago2-associated RNA, demonstrating that the process is initiat...
ORGANISM(S): Rattus norvegicus 
2015-03-02 | E-GEOD-57663 | biostudies-arrayexpress
UnknownMolecular detection of vector-borne and hemotropic pathogens in raccoons (<i>Procyon lotor</i>) from a tropical ecotourism area in Costa Rica.
Not available
S-EPMC12809098 | biostudies-literature
TranscriptomicsModulation of gene expression in cultured human intestinal colon explants by probiotic bacteria
Background: In the last decade, much attention has been drawn to probiotic bacteria in the context of inflammatory bowel disease (IBD), since the potential of certain strains to attenuate inflammation was demonstrated in several animal experiments and clinical studies. Data in humans elucidating the...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-23630 | biostudies-arrayexpress
UnknownMycobacterium tuberculosis Infection Induces BCSFB Disruption but No BBB Disruption In Vivo: Implications in the Pathophysiology of Tuberculous Meningitis.
Not available
S-EPMC9223849 | biostudies-literature
UnknownPhytochemical Profile, Vasodilatory and Biphasic Effects on Intestinal Motility, and Toxicological Evaluation of the Methanol and Dichloromethane Extracts from the Aerial Parts of Ipomoea purpurea Used in Traditional Mexican Medicine
Not available
S-EPMC12389191 | biostudies-literature
UnknownThe repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis.
Not available
S-EPMC11571740 | biostudies-literature
UnknownThe Effect of <i>Mucuna pruriens</i> on Depression-like Behavior Induced by a Mild Traumatic Brain Injury in Rats Is Associated with a Decrease in Brain Nitrite and Nitrate Levels.
Not available
S-EPMC12551065 | biostudies-literature
TranscriptomicsTranscription profiling of mouse VP16-CREB transgenics
Expression of VP16-CREB, a constitutively active form of CREB, in hippocampal neurons of the CA1 region lowers the threshold for eliciting the late, persistent phase of long-term potentiation (L-LTP) in the Schaffer collateral pathway. This VP16-CREB-mediated L-LTP differs from the conventional late...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3965 | biostudies-arrayexpress
UnknownMesenchymal stromal cells in human immunodeficiency virus-infected patients with discordant immune response: Early results of a phase I/II clinical trial.
Not available
S-EPMC7980217 | biostudies-literature
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