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GenomicsGenome-wide maps of Egr2 transcription factor binding sites in NKT and anti TCRb injected thymocytes.
We report the application of single-molecule-based sequencing technology for mapping the Egr2 transcriptional program in developing thymic NKT. We found that Egr2 controls the induction of genes required for NKT development. Examination of developing NKT cells and thymocytes receiving a strong TCR s...
ORGANISM(S): Mus musculus 
2012-02-06 | E-GEOD-34254 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-29-08-2014-08:27:40:831-1015 - samples
Whole-exome sequencing of a chronic lymphocytic leukemia (CLL) developed during vemurafenib treatment of a patient with malignant melanoma. Peripheral blood mononuclear cells were separated by Ficoll gradient centrifugation. DNA was extracted from highly purified (>97%) CD19+CD5+ cells obtained from...
EGAD00001000997 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-28-05-2015-11:13:32:451-82 - samples
Mutations that activate the RAF-MEK-ERK signaling pathway, in particular BRAFV600E, occur in many cancers, and mutant BRAF-selective inhibitors have clinical activity in these diseases. Activating BRAF alleles are usually considered to be mutually exclusive with mutant RAS, whereas inactivating muta...
EGAD00001001384 | EGA
UnknownPotassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery: The TIGHT K Randomized Clinical Trial.
Not available
S-EPMC11366075 | biostudies-literature
UnknownVaccine evaluation and genotype characterization in children infected with rotavirus in Qatar.
Not available
S-EPMC10382313 | biostudies-literature
UnknownPrevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study.
Not available
S-EPMC9094555 | biostudies-literature
UnknownEffects of Blended (Yellow) vs Forced Coagulation (Blue) Currents on Adverse Events, Complete Resection, or Polyp Recurrence After Polypectomy in a Large Randomized Trial.
Not available
S-EPMC8262363 | biostudies-literature
UnknownKetamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial.
Not available
S-EPMC11200139 | biostudies-literature
UnknownTranscriptional and clonal characterization of B cell plasmablast diversity following primary and secondary natural DENV infection.
Not available
S-EPMC7170960 | biostudies-literature
UnknownInitial Insights Into the Genetic Epidemiology of SARS-CoV-2 Isolates From Kerala Suggest Local Spread From Limited Introductions.
Not available
S-EPMC8010186 | biostudies-literature
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