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TranscriptomicsThe Menin-Bach2 axis is critical for regulating CD4 T cell senescence and cytokine homeostasis
Although CD4 T cell senescence plays an important role in immunosenescence, the mechanism behind this process remains unclear. Here we show that T cell-specific Menin deficiency results in the premature senescence of CD4 T cells, which is accompanied by the senescence-associated secretory phenotype...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-49968 | biostudies-arrayexpress
TranscriptomicsSimultaneous RNA-Seq Analysis of a Mixed Transcriptome of Rice and Blast Fungus Interaction
To understand the plant-pathogen interaction comprehensively, it is valuable to monitor the gene expression profiles of both interacting organisms simultaneously in the same infected plant tissue. Using RNA-Seq, we analyzed the mixed transcriptome of rice and blast fungus in infected leaves at 24 ho...
ORGANISM(S): Oryza sativa Japonica Group 
2012-12-14 | E-MTAB-4287 | biostudies-arrayexpress
ProteomicsProteome analysis of human postmortem brain tissues in tauopathies, including corticobasal degeneration, progressive supranuclear palsy, and Alzheimer's disease
Tauopathies are a group of neurodegenerative diseases characterised by the abnormal accumulation of tau protein within neural and glial cells. The molecular mechanisms of tauopathies remain poorly understood. To identify proteins whose abundance is altered by the disease group, we performed a proteo...
ORGANISM(S): Homo Sapiens (human) 
2026-05-09 | PXD072806 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set07
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004835 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set06
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004834 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set02
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004830 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set03
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004831 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set05
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004833 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set04
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004832 | JPOST Repository
ProteomicsMatsumoto_Verification of MRM assays using in vitro proteome
MS/MS spectra assigned to peptides with more than six amino acids were selected from our database and converted into MRM transitions. Overlapping ions with a difference in mass/charge ratio (m/z) of 400 were preferentially selected
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004902 | JPOST Repository
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