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TranscriptomicsExpression Data from Allogeneic Human Mesenchymal Stem Cells and Primary Cultures of Human Alveolar Epithelial Type II Cells
Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a severe syndrome affecting more than 200,000 patients annually in the U.S. New studies are needed to understand the biological and clinical mechanisms that impair alveolar epithelial function. Also, innovative therapies are ...
ORGANISM(S): Homo sapiens 
2015-07-08 | E-GEOD-68610 | biostudies-arrayexpress
UnknownClinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma.
Not available
S-EPMC3675667 | biostudies-literature
ProteomicsIn Vivo Protein Turnover Rates in Varying Oxygen Tensions Nominate MYBBP1A as a Novel Mediator of the Hyperoxia Response
Oxygen deprivation and excess are both toxic to mammals. Thus, the ability to adapt to varying oxygen tensions is critical for survival. While the transcriptional response to acute hypoxia has been well-studied, the post-translational effects of hypoxia and hyperoxia have been underexplored. In this...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-06-04 | MSV000092095 | MassIVE
ProteomicsOxygen Toxicity Causes Cyclic Damage by Destabilizing Specific Fe-S Cluster-Containing Protein Complexes
Oxygen is toxic across all three domains of life. Yet, the underlying molecular mechanisms remain largely unknown. Here, we systematically investigate the major cellular pathways affected by excess molecular oxygen. We find that hyperoxia destabilizes a specific subset of Fe-S cluster (ISC)-containi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-05 | MSV000091206 | MassIVE
UnknownPhenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.
Not available
S-EPMC9359694 | biostudies-literature
UnknownFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
Not available
S-EPMC10764789 | biostudies-literature
GenomicARDSnet and the iSPAAR Consortium: Genetic Studies

Acute Respiratory Distress Syndrome (ARDS)/ Acute Lung Injury (ALI) is a syndrome defined by the presence of acute hypoxemic respiratory failure, bilateral pulmonary infiltrates on chest radiograph, a known clinical risk factor (e.g. sepsis, pneumonia, trauma, gastric fluid aspiration, pancreatit...

phs000631 | dbGaP
UnknownEfficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial.
Not available
S-EPMC9384272 | biostudies-literature
UnknownThe Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19.
Not available
S-EPMC9447373 | biostudies-literature
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