Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse vehicle and sAPPalpha-treated hippocampal slice cultures
Gene expression changes induced by alpha-secretase cleaved amyloid precursor protein (sAPPalpha) in organotypic hippocampal slice cultures of male, postnatal day 15 mice (C57B6/SJL). Hippocampal slice cultures were treated with phosphate buffered saline (GSM26700, GSM26701, GSM26702) or 1 nM sAPPal...
ORGANISM(S): Mus musculus 
2007-10-10 | E-GEOD-1555 | biostudies-arrayexpress
TranscriptomicsA High-Fat Diet and NAD+ Rescue Premature Aging in Cockayne Syndrome
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in the genes encoding the DNA repair proteins CSA or CSB. Csbm/m mice were given a high-fat, caloric-restricted or resveratrol-supplemented diet. The high-fat diet rescued the p...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-62194 | biostudies-arrayexpress
UnknownMetabolic and molecular framework for the enhancement of endurance by intermittent food deprivation.
Not available
S-EPMC5998977 | biostudies-literature
TranscriptomicsCHD5, A Brain-Specific Chromatin Remodeling Enzyme, Regulates Expression Of Neuronal Genes.
CHD5 is frequently deleted in neuroblastoma, and appears to be a tumor suppressor gene; however, little is known about the role of CHD5. We found CHD5 mRNA was restricted to brain; by contrast most other remodeling ATPases were broadly expressed. CHD5 protein isolated from mouse brain was associat...
ORGANISM(S): Rattus norvegicus 
2011-09-21 | E-GEOD-27620 | biostudies-arrayexpress
TranscriptomicsExpression data from ARPE-19 cells treated with LDL or ox-LDL
LDL or Ox-LDL 200ug/ml, which showed no loss of viability after a 48 hour exposure, induced a physiological and pathological transcriptional response, respectively. LDL induced a downregulation of genes associated with cholesterol biosynthesis while ox-LDL induced transcriptional alterations in gene...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-GEOD-5741 | biostudies-arrayexpress
UnknownhnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies.
Not available
S-EPMC2908492 | biostudies-literature
TranscriptomicsAge Map, Cerebellum (A)
To assess the transcriptional changes in different brain regions and spinal cord associated with aging and either a caloric restricted (CR) or ad libitum (AL) diet. cDNA microarray and quantitative PCR analyses were used to examine the transcriptomes of various neuronal tissues in young, middle aged...
ORGANISM(S): Mus musculus 
2009-06-21 | E-GEOD-8409 | biostudies-arrayexpress
UnknownCombination Therapy with Low-Dose IVIG and a C1-esterase Inhibitor Ameliorates Brain Damage and Functional Deficits in Experimental Ischemic Stroke.
Not available
S-EPMC5908217 | biostudies-literature
UnknownRandomised controlled trial of intermittent vs continuous energy restriction during chemotherapy for early breast cancer.
Not available
S-EPMC9023522 | biostudies-literature
UnknownDNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease.
Not available
S-EPMC5242308 | biostudies-literature
Sort   by:  
 Page size