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ProteomicsMaxQuant.Live enables enhanced selectivity and identification of peptides modified by endogenous SUMO and ubiquitin
Small ubiquitin-like modifiers (SUMOs) and ubiquitin are frequent post-translational modifications of proteins that play pivotal roles in all cellular processes. We previously reported mass spectrometry-based proteomics methods that enable profiling of lysines modified by endogenous SUMO or ubiquiti...
ORGANISM(S): Homo sapiens (Human) 
2021-02-05 | PXD022367 | Pride
Peptide mass filtering Sumo Mql Ubiquitin Maxquant.live Precursor untargeting 
ProteomicsMaxQuant.Live enables global targeting of more than 25,000 peptides
Mass spectrometry (MS)-based proteomics is generally performed in a shotgun format, in which as many peptide precursors as possible are selected from full or MS1 scans so that their fragment spectra can be recorded in MS2 scans. While achieving great proteome depths, shotgun proteomics cannot guaran...
ORGANISM(S): Homo sapiens (Human) 
2019-02-27 | PXD011225 | Pride
Proteomics Mass spectrometry 
UnknownMaxQuant.Live Enables Global Targeting of More Than 25,000 Peptides.
Not available
S-EPMC6495250 | biostudies-literature
ProteomicsThe Hidden Culprit of Visceral Fat: Dysfunctional Subcutaneous Adipose Tissue – Adipose tissue proteomics
To investigate the proteomic profiles of paired subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) samples, as well as their correlations with clinical traits in severely obese patients, and to identify potential serum protein markers associated with tissue expression or metabolic s...
ORGANISM(S): Homo sapiens (Human) 
2023-10-16 | PXD041721 | Pride
Adipose tissue  visceral adipose tissue  subcutaneous adipose tissue  obesity  proteomics  type 2 diabetes 
ProteomicsSerum proteomics profiling identifies a signature for lung cancer early diagnosis
Lung cancer is the most common cause of death from cancer worldwide, largely due to frequent late diagnosis. Thus, there is the urgent need to develop new approaches to improve theearly detection of lung cancer, which would greatly affect patient survival. The quantitative protein expression profil...
ORGANISM(S): Homo sapiens (Human) 
2023-02-13 | PXD034221 | Pride
Early diagnosis Serum Microvesicles Lung cancer Biomarker 
ProteomicsAn Omics approach on Marchantia polymorpha single FERONIA and MARIS homologs confirms links between cell wall integrity and abscisic acid
Plant cells are surrounded by an extracellular cell wall that shields them from their abiotic and biotic environment. To coordinate their growth with their cell wall status, they have developed cell wall integrity mechanisms at the center of which lies the transmembrane Malectin-like receptor kinase...
ORGANISM(S): Marchantia polymorpha 
2024-11-27 | PXD058089 | Pride
Abscisic acid Cell wall integrity Malectin-like receptor kinases Marchantia Feronia Maris 
ProteomicsActive protein ubiquitination regulates xylem vessel functionality
Xylem vessels function in the long-distance conduction of water in land plants. The NAC transcription factor VASCULAR-RELATED NAC-DOMAIN7 (VND7) is a master regulator of xylem vessel cell differentiation in Arabidopsis (Arabidopsis thaliana). We previously isolated seiv (suppressor of ectopic xylem ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-10-17 | PXD048830 | Pride
Vnd7 Xylem vessel Ubiquitination 
ProteomicsGrafting systems for plant cadmium research: insights for basic plant physiology and applied mitigation
Cadmium (Cd) is a highly toxic and carcinogenic pollutant that poses a threat to human and animal health by affecting several major organ systems. Urbanization and human activities have led to significant increases in Cd concentration in the environment, including in agroecosystems. To protect again...
ORGANISM(S): Solanum lycopersicum 
2023-06-26 | PXD041184 | Pride
Abiotic stress  cadmium mitigation  environmental research  heavy metals  plant grafting  stress tolerance 
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