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TranscriptomicsGlioblastoma microvesicles transport RNA and proteins
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells. By incorporating an mRNA for a reporter protein into these microvesicles, we demonstrate th...
ORGANISM(S): Homo sapiens 
2008-11-15 | E-GEOD-13470 | biostudies-arrayexpress
TranscriptomicsMacrophage Microvesicles Induce Macrophage Differentiation and miR-223 Transfer
Microvesicles (MV) are small membrane-bound particles comprised of exosomes and various sized extracellular vesicles. These are released by a number of cell types. Microvesicles have a variety of cellular functions from communication to mediating growth and differentiation. Microvesicles contain pro...
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-41889 | biostudies-arrayexpress
TranscriptomicsmiRNA profiles of adipocyte-derived microvesicles (ADMs)
miRNA profiles of adipocyte-derived microvesicles (ADMs) on the Day 2-4 and Day 8-10 were compared. ADMs were prepared from the 48h-conditioned medium of 3T3-L1 adipocytes (Day 2-4 and Day 8-10) followed by RNA isolation.
ORGANISM(S): Mus musculus 
2010-07-06 | E-GEOD-17977 | biostudies-arrayexpress
TranscriptomicsAnalysis of tumor cell RNA (glioma and melanoma) and their corresponding microvesicles
Primary glioblastoma cells and primary malignant melanoma cells were grown in vitro (less than 15 passages). Exosomes/microvesicles were isolated from the media supernatant at the same time as RNA was extracted from the cells. The goal of the study was to compare the gene expression profiles in exos...
ORGANISM(S): Homo sapiens 
2012-01-31 | E-GEOD-35444 | biostudies-arrayexpress
ProteomicsCirculating Microvesicles and Exosomes in Small Cell Lung Cancer by Quantitative Proteomics
Early detection of small cell lung cancer crucially demands highly reliable markers. Growing evidence suggests that extracellular vesicles carry tumor cell-specific cargo suitable as protein markers in cancer. Therefore, we isolated plasma-derived microvesicles from newly diagnosed small cell lung c...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD028944 | Pride
Human Plasma Lc-ms/ms Extracellular vesicles 
TranscriptomicsGlioblastoma microvesicles transport RNA and proteins
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells. By incorporating an mRNA for a reporter protein into these microvesicles, we demonstrate th...
ORGANISM(S): Homo sapiens 
2008-11-16 | GSE13470 | GEO
ProteomicsPathophysiology of arterial cardiovascular events in patients with JAK2V617F myeloproliferative neoplasms
Cardiovascular events are the leading cause of death in patients with JAK2V617F myeloproliferative neoplasms. Their mechanisms are poorly understood. To investigate the role of microvesicles in these events, we performed a proteomic analysis of microvesicles derived from red blood cells from mice w...
ORGANISM(S): Mus musculus (Mouse) 
2020-02-17 | PXD014451 | Pride
Red blood cells Myeloproliferative neoplasms Mouse Microvesicles Jak2v617f 
ProteomicsProteomics of cerebrospinal fluid microvesicles
Comprehensive proteomic dataset of cerebrospinal fluid (CSF) microvesicles. The aim of this study is to deeply characterize the protein content of microvesicles (MVs) isolated from human cerebrospinal fluid. MVs were isolated from Two CSF pools and their proteome was studied with high sensitivity ma...
ORGANISM(S): Homo sapiens (Human) 
2014-05-07 | PXD000608 | Pride
Exosomes Microvesicles Cerebrospinal fluid Qexactive 
TranscriptomicsCultured fibroblasts treated with microvesicles from cardiomyocytes
Investigation of microvesicles exocytosed by cardiomyocytes. The aims of the study were to determine if microvesicles from cardiomyocytes are capable of affecting fibroblasts and causes changes in gene expression. The study showed that cardiomyocytes microvesicles are capable to cause change in gene...
ORGANISM(S): Mus musculus 
2011-11-01 | GSE21677 | GEO
GenomicsRNA sequencing of neutrophils treated with microvesicles derived from glucose-deprived hepatocellular carcinoma cells.
RNA sequencing of neutrophils treated with microvesicles derived from glucose-deprived hepatocellular carcinoma cells.
PRJNA1193659 | ENA
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