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Transcriptomics5' Cap-Isolated RNA Pol II Transcripts and ENCODE Tiling Arrays to Identify Gene Expression Changes in Hepatitis C Liver
Recent studies of the human transcriptome suggest that many transcripts have short or lack 3' poly(A) ends. In addition, the length of 3' poly(A) ends may vary for some transcript to regulate mRNA translation. Heterogeneous lengths of poly(A) ends may introduce variations in measuring RNA transcript...
ORGANISM(S): Homo sapiens 
2011-03-29 | E-GEOD-18904 | biostudies-arrayexpress
TranscriptomicsPronounced and Extensive Microtubule Defects in a Saccharomyces cerevisiae DIS3 Mutant
The recently proposed exozyme hypothesis posits that subunits of the RNA processing exosome assemble into structurally distinct protein complexes that function in disparate cellular compartments and RNA metabolic pathways. Here, in a genetic test of this hypothesis, we examine the role of Dis3 -- a...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-01 | E-GEOD-29018 | biostudies-arrayexpress
ProteomicsGlobal protein analysis of pediatric acute leukemia patients and matched xenografts
Proteomics reveal protein stability after xenotransplantation in murine models. Tryptic peptide digests from patient mononuclear cells were analyzed by Data Independent Acquisition (DIA) mass spectrometry. High-pH fractionation was performed on a pool of samples, followed by data dependent acquisiti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-02 | MSV000084646 | MassIVE
ProteomicsN terminome analysis of pediatric acute leukemia patients and matched xenografts
Proteomics reveal PTM stability after xenotransplantation in murine models. N termini enriched using HUNTER technique were analyzed by Data Independent Acquisition (DIA) mass spectrometry. High-pH fractionation was performed on a pool of samples, followed by data dependent acquisition (DDA) mass spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-02 | MSV000084643 | MassIVE
ProteomicsPhosphoproteome analysis of pediatric acute leukemia patients and matched xenografts
Proteomics reveal PTM stability after xenotransplantation in murine models. Phosphopeptides enriched using magnetic FeNTA beads were analyzed by Data Independent Acquisition (DIA) mass spectrometry. High-pH fractionation was performed on a pool of samples, followed by data dependent acquisition (DDA...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-02 | MSV000084645 | MassIVE
UnknownReliability and validity of PROMIS physical function, pain interference, and fatigue as patient reported outcome measures in adult idiopathic inflammatory myopathies: International study from the OMERACT myositis working group.
Not available
S-EPMC10354786 | biostudies-literature
UnknownResponsiveness and meaningful thresholds of PROMIS pain interference, fatigue, and physical function forms in adults with idiopathic inflammatory myopathies: Report from the OMERACT Myositis Working Group.
Not available
S-EPMC11663439 | biostudies-literature
ProteomicsCell line xenograft experiment
Pediatric ALL cell line 380 was injected via tail vein into NSG mice. Triplicate 380 cell samples were also prepared at the timepoint of injection and stored at -80 oC for comparative analysis with CDXs. Mice were euthanized at onset of leukemia symptoms and spleen, bone marrow and liver samples wer...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-20 | MSV000086727 | MassIVE
UnknownClinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.
Not available
S-EPMC4843946 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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