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TranscriptomicsPulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed, carcinogenic environmental contaminants produced as a consequence of the incomplete combustion of fossil fuels. Benzo[a]pyrene (BaP) is a very extensively studied prototypical PAH. We recently reported a complete lack of change in micro...
ORGANISM(S): Mus musculus 
2011-10-03 | E-GEOD-24751 | biostudies-arrayexpress
MetabolomicsUltra-High Mass Resolving Power, Mass Accuracy, and Dynamic Range MALDI Mass Spectrometry Imaging by 21-T FT-ICR MS

Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy and dynamic range. Fourier transform ion cyclotron resonance mass sp...

2022-01-28 | MTBLS3154 | MetaboLights
TranscriptomicsTranscription profiling by array of human non-activated MM6 cells with cyclin T1 knockdown
Cyclin T1-dependent genes in LPS-activated MM6 cells. HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II ...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10738 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human parental MM6 cell response to lipoloysaccharide and phorbal ester
Parental MM6 cells, as an additional control, were treated with LPS and PMA. Genes affected by the treatments were identified. HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One cr...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10739 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human PMA-activated Jurkat cells
Cyclin T1-dependent genes in activated Jurkat cells. HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II el...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10232 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human LPS-activated MM6 cells with Cyclin D1 knockdown
Cyclin T1-dependent genes in LPS-activated MM6 cells. HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II e...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10234 | biostudies-arrayexpress
TranscriptomicsCTDG in PMA-activated MM6 cells
Cyclin T1-dependent genes in PMA-activated MM6 cells. HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4+ T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II e...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-10233 | biostudies-arrayexpress
TranscriptomicsExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Background: Skin aging is associated with intrinsic processes that compromise structure of the extracellular matrix while promoting loss of functional and regenerative capacity. These processes are accompanied by a large-scale shift in gene expression, but underlying mechanisms are not understood an...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-35322 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in resting human skeletal muscle of sedentary and highly-trained individuals.
We used gene microarray analysis to compare the global expression profile of genes involved in adaptation to exercise training in skeletal muscle from chronically strength/resistance trained (ST), endurance trained (ET) and untrained control subjects (Con). Resting skeletal muscle samples (~100mg) ...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-9405 | biostudies-arrayexpress
TranscriptomicsEthylene and 1-MCP differentially regulate gene expression during onion (Allium cepa L.) sprout suppression
Onion is regarded as non-climacteric. In onion, ethylene can suppress sprouting however, the ethylene binding inhibitor, 1-MCP can also suppress sprout growth although it is unknown how ethylene and 1-MCP elicit the same response. In this study, onion bulbs were treated with 10 μL L-1 ethylene or 1...
ORGANISM(S): Allium cepa 
2011-06-29 | E-GEOD-27132 | biostudies-arrayexpress
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