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ProteomicsTDP-43-stratified single-cell proteomic profiling of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis
Single cell dataset of human motor neurons laser-captured from postmortem ALS and control tissues (1) ALS Pilot dataset (2) TDP43 stratified dataset Summary: Unbiased proteomics has been employed to interrogate central nervous system (CNS) tissues (brain, spinal cord) and fluid matrices (CSF, plas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-07 | MSV000092119 | MassIVE
TranscriptomicsGene expression data from human metastatic melanoma tumors that may predict response to RAF265
To determine how mutation of BRAF affected the response to RAF265, we utilized a tumor orthotopic implant model of early passage melanoma tumors in nude mice from a series of 17 patients with advanced metastatic Tumor growth was compared between RAF265 treatment (40 mg/kg, QD) and diluent control gr...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-30812 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica virulent and nonvirulent entamoeba species
Entamoeba histolytica is a protozoan parasite that causes colitis and liver abscesses. Several Entamoeba species and strains with differing levels of virulence have been identified. E. histolytica HM-1:IMSS is a virulent strain, E. histolytica Rahman is a nonvirulent strain, and Entamoeba dispar is ...
ORGANISM(S): Entamoeba histolytica 
2006-01-03 | E-SMDB-3589 | biostudies-arrayexpress
ProteomicsNrf2 is a central regulator of the metabolic landscape in macrophages and finetunes their inflammatory response
To overcome oxidative, inflammatory, and metabolic stress, cells have evolved networks of cytoprotective proteins controlled by transcription factor nuclear factor erythroid 2 p45-related factor 2 (Nrf2) and its main negative regulator the Kelch-like ECH associated protein 1 (Keap1). Here, we used h...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-13 | PXD027737 | Pride
Tmt Keap1 Nrf2 Mitochondria Bmdm Murine 
UnknownRapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.
Not available
S-EPMC5932240 | biostudies-literature
UnknownStoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Not available
S-EPMC10549897 | biostudies-literature
GenomicsHighly integrated single base resolution maps of the epigenome in Arabidopsis
Whole genome shotgun bisulfite sequencing, small RNA sequencing and transcriptome sequencing of wildtype Arabidopsis plants (Col-0), and met1, drm1 drm2 cmt3, and ros1 dml2 dml3 null mutants using the Illumina Genetic Analyzer. A comparison was performed with regions of the genome containing cytosin...
ORGANISM(S): Arabidopsis thaliana 
2008-04-20 | E-GEOD-10877 | biostudies-arrayexpress
MetabolomicsTrace elements and lipidomic datasets of stranding samples in the blubber of Turpsios truncatus from the Yucatan Coast: Association with biological features
Trace elements are the result of natural and anthropogenic sources. Some of them are toxic causing alterations in the properties of membranes and produce lipid peroxidation. The dataset presented here is associated with the research article paper entitled “Trace element and lipidomic analysis of bot...
2022-10-24 | MTBLS5772 | MetaboLights
UnknownDecreased parasite burden and altered host response in children with sickle cell anemia and severe anemia with malaria.
Not available
S-EPMC8759120 | biostudies-literature
TranscriptomicsMethylation profiling of normal and cancerous breast cells from human patients and cell lines in a 125 kB region of the HOXA cluster
To evaluate DNA methylation profile associated with breast cancer in 125 kB region of HOXA cluster we analyzed DNA from normal cancerous breast specimens and cell lines. Analysis was performed on the tiling array covering entire HOXA region with 500bp resolution. Immunoprecipitation with anti-methyl...
ORGANISM(S): Homo sapiens 
2006-11-03 | E-MEXP-880 | biostudies-arrayexpress
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