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ProteomicsPurification of human plasma exosomes for proteomics: optimization and application to detect changes in response to exercise
Extracellular vesicles (EVs) are released into blood from multiple organs and carry molecular cargo that facilitates inter-organ communication and an integrated response to physiological and pathological stimuli. Interrogation of the protein cargo of EVs is currently limited by the absence of optim...
ORGANISM(S): Homo sapiens (Human) 
2021-08-09 | PXD026483 | Pride
Ultracentrifugation High intensity exercise Mass spectrometry Size-exclusion chromatography Bioinformatics 
UnknownDevelopment of advanced conduction disturbances following balloon-expandable transcatheter aortic valve replacement leads to poorer clinical outcomes.
Not available
S-EPMC7411204 | biostudies-literature
UnknownDevelopment and validation of the Ulcerative Colitis patient-reported outcomes signs and symptoms (UC-pro/SS) diary.
Not available
S-EPMC5976680 | biostudies-literature
GenomicPROstate Cancer Medically Optimized Genome Enhanced ThErapy (PROMOTE)

The Prostate Cancer Medically Optimized Genome-Enhanced Therapy (PROMOTE) study uses genetic clues in castration-resistant prostate cancer that may identify an individualized treatment approach for men with the disease.

Understanding the molecular biology behind castration-resistant prosta...

phs001141 | dbGaP
GenomicsA Genome-Wide Association Study of Peripheral Arterial Disease

The Electronic Medical Record Phenotypes and Community-engaged Genomic Association Study aims to identify genetic variants mediating susceptibility to peripheral arterial disease (PAD). The study leverages a biorepository of blood samples of 1688 PAD cases and 1649 controls, and the electronic ...

phs000203.v1.p1 | EGA
UnknownGait, balance, and patient-reported outcomes during taxane-based chemotherapy in early-stage breast cancer patients.
Not available
S-EPMC5510549 | biostudies-literature
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownFeasibility of capturing real-world data from health information technology systems at multiple centers to assess cardiac ablation device outcomes: A fit-for-purpose informatics analysis report.
Not available
S-EPMC8449615 | biostudies-literature
UnknownThe establishment of the GENEQOL consortium to investigate the genetic disposition of patient-reported quality-of-life outcomes.
Not available
S-EPMC2824176 | biostudies-literature
UnknownProspective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.
Not available
S-EPMC8462523 | biostudies-literature
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