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ProteomicsPredictive protein biomarker signatures and the corresponding transcriptional cell state changes in human lung fibrosis (Plasma)
Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within reach. However, the correspondence of peripheral protein signatures to changes in cell state in diseased organs is c...
ORGANISM(S): Homo sapiens (Human) 
2020-09-18 | PXD017210 | Pride
Data integration Proteomics Fibrosis Single cell rna-seq Systems medicine Biomarker 
ProteomicsSwarms of specialized fibroblasts drive scarring through N-cadherin
Injury in mammals induces a connective tissue response to either regenerate as before, or to scar. The fibroblastic actions and mechanisms that underlie these connective tissue responses remain obscure, as direct observation in animals is too difficult and current assays do not faithfully reproduce ...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-26 | PXD016068 | Pride
Live imaging Collective migration Fibroblastic swarm Cell lineage Contraction Scad Scarring Scar progenitors N-cadherin 
ProteomicsPredictive protein biomarker signatures and the corresponding transcriptional cell state changes in human lung fibrosis
Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within sight. However, the correspondence of peripheral protein signatures with cell state changes in diseased organs is cu...
ORGANISM(S): Homo sapiens (Human) 
2020-09-18 | PXD017145 | Pride
Data integration Proteomics Fibrosis Single cell rna-seq Systems medicine Biomarker 
ProteomicsM.musculus - Lung, iBAQ (Angelidisetal,natcommun.2019)
abundance based on iBAQ, Interaction consistency score: 9.7, Coverage: 21
ORGANISM(S): 10090 
2019-00-00 | 3284560666 | PAXDB
ProteomicsM.musculus - Lung, iBAQ (Angelidisetal,natcommun.2019)
abundance based on iBAQ, Interaction consistency score: 8.7, Coverage: 21
ORGANISM(S): 10090 
2019-00-00 | 386924191 | PAXDB
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