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TranscriptomicsExpression data during plantaris muscle hypertrophy with/without satellite cells induced by synergist ablation in young adult Pax7-DTA mice
Global gene expression patterns were determined from microarray results from sham surgery or following 1 week of plantaris muscle hypertrophy induced by synergist ablation in young adult Pax7-DTA mice (4 months). Vehicle treated mice have their full complement of satellite cells; tamoxifen treated m...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-52597 | biostudies-arrayexpress
UnknownSignificant improvement in survival after allogeneic hematopoietic cell transplantation during a period of significantly increased use, older recipient age, and use of unrelated donors.
Not available
S-EPMC3691359 | biostudies-literature
MetabolomicsA general non-self response as part of plant immunity
Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...
2021-09-13 | MTBLS2522 | MetaboLights
UnknownGenome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia.
Not available
S-EPMC3398986 | biostudies-literature
ProteomicsAnalysis of total proteome changes upon long-term treatment with Rho kinase inhibitor H1152.
We quantified protein changes associated with long-term Rho-kinase inhibition, using SILAC proteomics in conjugation with long-termH1152 treatment of mouse embryonic fibroblast cells.
ORGANISM(S): Mus musculus (Mouse) 
2016-01-18 | PXD002521 | Pride
Mouse embryonic fibroblasts  rock1/2  h1152  silac  cell cycle 
ProteomicsTemporal analysis of phospho-proteome changes following Rho-kinase inhibition.
To define short and long-term changes in the phospho-proteome of the cells following Rho-kinase inhibition with H1152 inhibitor, in mouse embryonic fibroblast cells.
ORGANISM(S): Mus musculus (Mouse) 
2016-01-18 | PXD002515 | Pride
Mouse embryonic fibroblasts  rock1/2  phospho-myosin light chain  h1152 
ProteomicsProtrusion vs Cell-body pulsed-SILAC proteomics
In mesenchymal-like cell migration, cells need to polarise into a protrusive front and a retracting cell body. Apart from proteins, several mRNAs are known to be localised to cell protrusions but to what extent RNA localisation and local translation contributes toward front-back assymetry is unknown...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2015-10-09 | PXD002649 | Pride
Pulsed-silac  local translation  protrusion 
ProteomicsProtrusion vs Cell-body SILAC proteomics
In mesenchymal-like cell migration, cells need to polarise into a protrusive front and a retracting cell body. To understand this process better, we set out to quantify the distribution of cellular proteins between protrusions and cell-body by proteomics, using MDA-MB-231 cells, a highly invasive br...
ORGANISM(S): Homo sapiens (Human) 
2015-10-09 | PXD000914 | Pride
Human silac proteomics protrusion lc-ms/ms orbitrap-velos maxquant 
TranscriptomicsComparing the transcriptome profiling of ob/ob mice treated with the GLP-1 receptor agonist liraglutide, a clinically used GLP-1 receptor agonist, versus baseline controls
B6.Cg-Lep ob/ob mice females were surgically implanted in an age of 10-12 weeks with Alzet osmotic mini pumps (model 1002, 0,25l/h, Cupertino, CA, USA) in two groups of ten mice each to perform continuous subcutaneous infusions of Dulbecco's phosphate buffered saline (vehicle; n = 8) or GLP-1 (GLP-1...
ORGANISM(S): Mus musculus 
2017-09-03 | E-MTAB-6015 | biostudies-arrayexpress
GenomicsEGAS00001000462-sc-20170511 - samples
The offspring of first cousin marriages have ~6% of their genome autozygous, i.e. homozygous identical by descent, or even more if there was further consanguinity in their ancestry. In the UK there are large populations with very high first cousin marriage rates of 20-50%. Sequencing the exomes of...
EGAD00001003329 | EGA
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