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TranscriptomicsNegative energy balance and hepatic gene expression patterns in high yielding dairy cows during the early postpartum period [liver]
In high yielding dairy cows the liver undergoes extensive physiological and biochemical changes during the early postpartum period in an effort to re-establish metabolic homeostasis and to counteract the adverse effects of negative energy balance (NEB). These adaptations are likely to be mediated by...
ORGANISM(S): Bos taurus 
2014-04-08 | E-GEOD-56547 | biostudies-arrayexpress
TranscriptomicsArgonaute2 mediates compensatory expansion of the pancreatic M-CM-^_-cell
Pancreatic M-CM-^_-cells adapt to compensate for the increased metabolic demand during insulin resistance. While the microRNA pathway has an essential role in the expansion of M-CM-^_-cell mass, the extent of its contribution is unclear. Here we show that miR-184 is silenced in the pancreatic islets...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-46623 | biostudies-arrayexpress
TranscriptomicsNegative energy balance and splenic gene expression patterns in high yielding dairy cows during the early postpartum period [spleen]
Increased energy demands to support lactation, coupled with lowered feed intake capacity results in negative energy balance (NEB) and is typically characterized by extensive mobilization of body energy reserves in the early postpartum dairy cow. The catabolism of stored lipid leads to an increase i...
ORGANISM(S): Bos taurus 
2014-04-08 | E-GEOD-56589 | biostudies-arrayexpress
UnknownHealth Care Segregation, Physician Recommendation, and Racial Disparities in BRCA1/2 Testing Among Women With Breast Cancer.
Not available
S-EPMC5012689 | biostudies-literature
TranscriptomicsExpression profiles of primary bone marrow derived mouse macrophages M-bM-^@M-^S untreated and treated with LPS or LPS+PGE
The polarization of macrophages into an anti-inflammatory or regulatory phenotype plays an important role in resolving inflammation. PGE2 regulates macrophage polarization via a PKA dependent pathway. PKA phosphorylates SIKs, inhibiting their ability to phosphorylate CRTC3 in cells. This in turn ...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-41833 | biostudies-arrayexpress
TranscriptomicsThe MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs
Piwi-interacting RNAs (piRNAs) guide Piwi Argonautes to suppress transposon activity in animal gonads. Known piRNA populations are extremely complex, with millions of individual sequences present in a single organism. Despite this complexity, specific Piwi proteins incorporate piRNAs with distinct n...
ORGANISM(S): Bombyx mori 
2014-07-01 | E-GEOD-55451 | biostudies-arrayexpress
UnknownA Synergistic Approach to Atmospheric Water Scavenging.
Not available
S-EPMC10032561 | biostudies-literature
UnknownConsidering sex as a biological variable in preclinical research.
Not available
S-EPMC6191005 | biostudies-literature
UnknownEndothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress.
Not available
S-EPMC5714503 | biostudies-literature
UnknownLong terminal repeat retrotransposons of Mus musculus.
Not available
S-EPMC395764 | biostudies-literature
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