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The discovery of KRAS G12C inactive state inhibitors represents a significant advancement in the field of precision oncology. While inactive state inhibition shows promise in patients, SWII-binding inhibitors targeting both inactive and active states remain an underdeveloped therapeutic modality. H...
ORGANISM(S): Homo sapiens (Human) 
2025-11-04 | PXD062227 | Pride
The study includes whole-genome bisulfite sequencing (WGBS) on 34 adipose (7 MZ pairs, 6 DZ pairs and 8 singletons) and 27 blood (7 MZ pairs, 6 DZ pairs and 1 singleton) DNA samples derived from a total of 43 female twins belonging to the MuTHER/TwinsUK cohort. We generated 11.5 billion 100bp paired...
Data Access Committee EGAC00001000402
Comprehensive analysis of the human adipose epigenome by transcriptome, open chromatin and methylome sequencing studies.
ORGANISM(S): Homo sapiens 
Comprehensive analysis of the human adipose epigenome by transcriptome, open chromatin and methylome sequencing studies.
ORGANISM(S): Homo sapiens 
WTCCC project samples from the Parkinson's disase cohort
Genome-wide association scan was performed in 1,705 cases of parkinson's genotyped on the Illumina Human 660W SNP array, and 5,175 controls genotyped on the Illumina1.2M-Duo. Analysis was carried out on the overlaps set of SNPs.
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