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ProteomicsA proteomic approach to identify vaccine candidates based on host cell attachment provides a novel protective Pseudomonas aeruginosa vaccine antigen: cell division protein, FtsZ
Pseudomonas aeruginosa is an opportunistic Gram negative pathogen that causes severe nosocomial infections in susceptible individuals due to the emergence of multi-drug resistant strains. There are no approved vaccines against P. aeruginosa infections nor candidates in active clinical development, h...
ORGANISM(S): Pseudomonas aeruginosa PA14 Bacteria 
2025-05-07 | PXD055823 | Pride
Antigens Pseudomonas aeruginosa Vaccine 
ProteomicsProteomic analysis of three independent series of sequential cystic fibrosis strains in an International Pseudomonas aeruginosa reference panel indicates positive selection in late infection strains.
Pseudomonas aeruginosa is a frequent cause of chronic opportunistic infections in people with cystic fibrosis (CF). It is a highly diverse and adaptable Gram-negative bacterium that thrives in many environments. It is well recognised that P. aeruginosa adapts over time of colonisation to facilitate ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 Bacteria 
2026-09-28 | PXD073355 | Pride
Pseudomonas aeruginosa  cystic fibrosis  adaptation  proteomics  stress responses 
ProteomicsCysteamine inhibits glycine utilisation and disrupts virulence in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a major opportunistic human pathogen which employs a myriad of virulence factors. In people with cystic fibrosis (CF) P. aeruginosa frequently colonises the lungs and becomes a chronic infection that evolves to become less virulent over time, but often adapts to favour pers...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2021-08-19 | PXD027156 | Pride
Pseudomonas aeruginosa Human 
UnknownCost savings with transcutaneous screening versus total serum bilirubin measurement for newborn jaundice in hospital and community settings: a cost-minimization analysis.
Not available
S-EPMC6182126 | biostudies-literature
UnknownIncreased Virulence of Bloodstream Over Peripheral Isolates of P. aeruginosa Identified Through Post-transcriptional Regulation of Virulence Factors.
Not available
S-EPMC6212473 | biostudies-literature
UnknownCo-located quantitative trait loci mediate resistance to Agrobacterium tumefaciens, Phytophthora cinnamomi, and P. pini in Juglans microcarpa × J. regia hybrids.
Not available
S-EPMC8087670 | biostudies-literature
ProteomicsBCAS0292 is involved in the adaptation of Burkholderia cenocepacia and shows characteristics of a DNA mimic protein WHOLE PROTEOME
Adaptation of opportunistic pathogens to their host environment requires reprogramming of a vast array of genes to facilitate host survival in the host. Burkholderia cenocepacia, a Gram-negative bacterium with a large genome of ~ 8Mb in size that colonizes environmental niches, is exquisitely adapta...
ORGANISM(S): Burkholderia cenocepacia Bacteria 
2022-01-11 | PXD030042 | Pride
Dna-protein interactions Burkholderia Host-pathogen interactions  respiratory infections  bacterial adaptation 
ProteomicsHypoxia decreases the pathogenicity of Pseudomonas aeruginosa by reducing expression of multiple virulence factors.
Hypoxia is a feature of the microenvironment during P. aeruginosa infection in several disease states. We confirm that the pathogenicity of P. aeruginosa derived from sites of acute infection is higher than those derived from sites of chronic infection. Hypoxia attenuated the pathogenicity of acute ...
ORGANISM(S): Pseudomonas aeruginosa str. E2UoS 
2017-06-06 | PXD004421 | Pride
Hypoxia Pseudomonas aeruginosa 
UnknownNeighbourhood-level material deprivation and response to combination antiretroviral therapy in the Canadian Observational Cohort (CANOC): a longitudinal cohort study.
Not available
S-EPMC8929426 | biostudies-literature
UnknownAspergillus fumigatus Inhibits Pseudomonas aeruginosa in Co-culture: Implications of a Mutually Antagonistic Relationship on Virulence and Inflammation in the CF Airway.
Not available
S-EPMC5996130 | biostudies-literature
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