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ProteomicsInterplay between nuclear tau phosphorylation and HSV-1 infection.
In this study, we investigated the effects of HSV-1 infection on tau phosphorylation in human brain cortical organoids. Our findings demonstrate that HSV-1 triggers nuclear accumulation of phosphorylated tau in neurons within the developing cortical plate as well as in neural precursor cells (NPCs) ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD047281 | Pride
Human Alzheimers Herpes simplex virus Neurodegenerative diseases Tau 
ProteomicsKinase Selectivity Profiling of anti-MRSA Diarylimidazoles in HEK293 Cells
Antimicrobial resistance (AMR) is widely acknowledged as one of the most serious public health threats facing the world, yet the private sector finds it challenging to generate much-needed medicines. As an alternative discovery approach, a small array of diarylimidazoles was screened against the ESK...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040208 | Pride
Diarylimidazole Mib-ms Kinases Hek293 Antimicrobials 
TranscriptomicsTranscription profiling of mouse pre-implantation development over twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst
The goal of the experiments was to profile and analyze gene activity during murine pre-implantation development. Samples were collected at twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst.
ORGANISM(S): Mus musculus 
2004-02-19 | E-MEXP-51 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Candida albicans populations exposed to a temperature shift from 25 degrees to 37 degrees
Seperate White and Opaque Candida albicans populations were exposed to a temperature shift from 25 degrees to 37 degrees. Samples were then harvested at various time points to follow the effects of the shift on the two cell types, particularly the opaque cell type which switches to the white cell ...
ORGANISM(S): Candida albicans 
2011-05-08 | E-MEXP-2705 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of C. albicans to identify the commintment point of the temperature induced opaque-to-white switch
This experiment is a characterization of the commitment point of the temperature induced opaque-to-white switch in the fungal pathogen Candida albicans. This experiment examines changes in the transcriptome occurring at the 50% commitment points for both the wild type and WOR1/wor1 strains in order...
ORGANISM(S): Candida albicans 
2011-07-07 | E-MEXP-2834 | biostudies-arrayexpress
GenomicsA Multiethnic Genome wide Scan of Prostate Cancer

Multiple GWA studies of prostate cancer conducted in European White populations are ongoing. These studies will continue to have a dramatic impact on our understanding of the contribution of common genetic variation on inter-individual susceptibility to this common cancer. Important questions tha...

phs000306.v3.p1 | EGA
TranscriptomicsGene expression changes during retinal development and rod specification.
Photoreceptor disorders are collectively known as retinal degeneration (RD), and include retinitis pigmentosa (RP), cone-rod dystrophy and age related macular degeneration (AMD). These disorders are largely genetic in origin; individual mutations in any one of >200 genes cause RD, making mutation sp...
ORGANISM(S): Mus musculus 
2015-01-20 | E-GEOD-59201 | biostudies-arrayexpress
UnknownProcalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission.
Not available
S-EPMC9070482 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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