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TranscriptomicsBulk RNA-seq of human first-trimester and term Hofbauer cells before and after in vitro culture for 7 days
To establish an in vitro assay using primary human Hofbauer cells, we needed to understand how the cells change in vitro. We therefore profiled and compared the transcriptomes of freshly isolated first-trimester and term Hofbauer cells to those after 7 days in culture. Cells were isolated by fluores...
ORGANISM(S): Homo sapiens 
2025-08-04 | E-MTAB-14087 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq profiling the response of human first-trimester and term Hofbauer cells to Listeria monocytogenes infection in vitro
To understand the response of human Hofbauer cells to Listeria monocytogenes infection and how it differs between first trimester and term, we established an infection assay using primary human first-trimester and term Hofbauer cells isolated by fluorescence-activated cell sorting and cultured in vi...
ORGANISM(S): Homo sapiens 
2025-08-04 | E-MTAB-14086 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of human macrophages and monocytes from first-trimester and term placentas
To understand how the human macrophages and monocytes (of both fetal and maternal origin) isolated from first-trimester and term placentas differ, we profiled and compared the transcriptomes of cells freshly isolated by fluorescence-activated cell sorting, including fetal Hofbauer cells, placenta-as...
ORGANISM(S): Homo sapiens 
2025-08-04 | E-MTAB-14088 | biostudies-arrayexpress
UnknownMultisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in male mice with Down Syndrome.
Not available
S-EPMC12021272 | biostudies-literature
TranscriptomicsTranscription profiling of CD14 monocytyes and CD16 neutrophils from patients with systemic lupus erythematosus
Copy number variation (CNV) has been shown to be common in regions of the genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity. Low copy number of FCGR3B has recently been associated with systemic lupus erythematosus (SLE). FcγRIIIb is a glycosylphosphatidylino...
ORGANISM(S): Homo sapiens 
2008-10-02 | E-TABM-463 | biostudies-arrayexpress
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