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CHEBI ID

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First Public Date

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Study type

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Lab affiliation

Associate Professor, Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center (1)
Clinical and Diagnostic Immunology, Department Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium (1)
Department of Biochemistry and Molecular Biology, Bio21 Institute, The University of Melbourne, Parkville, Victoria, Australia (1)
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GlaxoSmithKline (GSK) (1)
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Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK; Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany. (1)
Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, Scotland, UK Chair of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, Berlin, German (1)
Zentrum für Molekulare Biologie (ZMBH), Mass Spectrometry and Proteomics (1)

Tags

xref:PubMed:27760770 (1)

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Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer

We analyzed transcriptional changes in 4 prostate cancer cell lines following treatment with the BET inhibitor I-BET762 using Affymetrix Human Genome U133 Plus 2.0 Arrays. Four prostate cancer cell lines (NCI-H660, VCaP, LNCaP, PC-3) were treated with DMSO (control) or I-BET762 at 0.5uM or 10uM con...

ORGANISM(S): Homo sapiens

2014-03-31 | E-GEOD-56352 | biostudies-arrayexpress

RNA antisense purification with mass spectrometry (RAP-MS) experiment for identification of GRAS1 non-coding RNA interacting proteins

GRAS1 non-coding RNA is required for cell survival in A549 lung cancer cells. We identified the protein interactome of GRAS1 RNA using RAP-MS, then compared the results of the GRAS1 capture to captures of positive control U1 RNA and negative control luciferase RNA. Unique proteins binding specifical...

ORGANISM(S): Homo sapiens (Human)

2026-09-28 | PXD042699 | Pride