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TranscriptomicsRNA-seq of postnatal day 0 (P0) wild-type and Satb2-/- cortices
The goal of the study was to compare gene expression of P0 wild-type and P0 Satb2-/- cortices. Total RNAs were isolated from P0 cortices dissected from wild-type and Satb2-/- mice (n=3 for each genotype), following Qiagen RNAeasy kit instruction.Sequence libraries were made following Illumina RNA Tr...
ORGANISM(S): Mus musculus 
2015-09-08 | E-GEOD-68911 | biostudies-arrayexpress
GenomicsChIP-seq for Satb2 in E15 cortex
The goal of the study was to identify the binding site of SATB2 in wild-ype cortex by performing ChIP-seq using SATB2 antibody. E15 cortical tissues were dissected, lysed and fixed. Chromatin was prepared by sonication. Sequences bound by SATB2 protein was precipitated using a SATB2 antibody. Sequen...
ORGANISM(S): Mus musculus 
2015-09-08 | E-GEOD-68910 | biostudies-arrayexpress
GenomicsGenomic Analysis of Pediatric Low Grade Gliomas

Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart from mutations or duplications in the BRAF kinase in specific subclasses, few genetic driver events are known. Diffuse PLGGs compose a set of uncommon subtypes that exhibit invasive growth and are th...

phs000614.v1.p1 | EGA
TranscriptomicsGenomic analysis of diffuse pediatric low-grade gliomas identifies recurrent, oncogenic MYBL1-truncating rearrangements
Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but apart from BRAF mutations or duplications in specific subclasses, few genetic driver events are known. Diffuse PLGGs comprise a set of uncommon subtypes that exhibit invasive growth and are therefore especiall...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-45843 | biostudies-arrayexpress
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
UnknownPathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
Not available
S-EPMC7864894 | biostudies-literature
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