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TranscriptomicsThe transcriptional landscape of hematopoietic stem cell ontogeny
Transcriptome analysis of adult hematopoietic stem cells (HSC) and their progeny has informed our understanding of blood differentiation and leukemogenesis, but a similarly transformative analysis of the embryonic origins of hematopoiesis is lacking. To address this issue, we acquired gene expressi...
ORGANISM(S): Mus musculus 
2012-11-01 | E-GEOD-37000 | biostudies-arrayexpress
TranscriptomicsNfix is a novel regulator of murine hematopoietic stem and progenitor cell survival
Hematopoietic stem cells are both necessary and sufficient to sustain the complete blood system of vertebrates. Here we show that Nfix, a member of the nuclear factor I (Nfi) family of transcription factors, is highly expressed by hematopoietic stem and progenitor cells (HSPC) of murine adult bone ...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-45492 | biostudies-arrayexpress
TranscriptomicsFunctional screen for novel regulators of murine hematopoietic stem cell in vivo repopulating activity
Although Hematopoietic Stem Cell Transplantation (HSCT) routinely treats hematologic disease, many patients experience adverse outcomes. Understanding the molecular regulation of HSC engraftment is paramount to improving HSCT regimens. Here, we executed a large-scale transplant-based functional sc...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-63830 | biostudies-arrayexpress
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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