Sort   by:  
 Page size 
UnknownDelirium in Survivors of Cardiac Arrest Treated With Mild Therapeutic Hypothermia.

Background

Mild therapeutic hypothermia is recommended for comatose patients resuscitated from cardiac arrest. However, the prevalence of delirium and its associated risk factors have not been assessed in survivors of cardiac arrest treated with therapeutic hypothermia.

Objective

To d...
S-EPMC5240926 | biostudies-literature
UnknownGenome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease.
Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine, have recently been identified as novel risk factors for atherosclerosis in mice and humans. We sought to identify genetic factors associated with plasma betaine levels and determine their effect on ...
S-EPMC4740183 | biostudies-literature
UnknownDiabetes autoantibodies do not predict progression to diabetes in adults: the Diabetes Prevention Program.

Aims

To determine if the presence of diabetes autoantibodies predicts the development of diabetes among participants in the Diabetes Prevention Program.

Methods

A total of 3050 participants were randomized into three treatment groups: intensive lifestyle intervention, metformin and pl...
S-EPMC4138247 | biostudies-literature
UnknownSociodemographic, Clinical, and Psychosocial Predictors of Short- and Long-term Study Retention in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS).

Objective

Success of longitudinal studies depends on retention of participants. We examined characteristics as predictors of retention among participants with prediabetes and type 2 diabetes (T2D) in the Diabetes Prevention Program (DPP) and the follow-up DPP Outcomes Study.

Research desi...

S-EPMC12451849 | biostudies-literature
GenomicsABO_OICR_DATASET - samples
OICR PANCREATIC CANCER DATASET
EGAD00001000262 | EGA
GenomicsABO_OICR_DATASET_2 - samples
OICR PANCREATIC CANCER DATASET 2
EGAD00001000276 | EGA
GenomicsICGC_PACA-AU_20160429 - samples
Additional sequencing data for 173 donors in EGAS00001000154, a study of Pancreatic Ductal Adenocarcinoma. WGS libraries were used for high-cellularity cases, WXS sequencing to high depth on low-cellularity cases. HiSeq 2xxx platform was used in all cases. The analysis files associated with this dat...
EGAD00001002192 | EGA
UnknownNovel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.

Background

Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking behaviour and lung health.

Methods

We sampl...
S-EPMC4593935 | biostudies-literature
GenomicsGenome Landscape of Primary Pancreatic Ductal Adenocarcinoma
The purpose of the Australian ICGC Pancreatic Cancer Genome Sequencing Initiative study is to identify the common driving mutations underlying the initiation and development of Pancreatic Adenocarcinoma in a large cohort of pancreatic cancer patients (n=350). Matched genome sequences will be generat...
EGAS00001000154 | EGA
UnknownIdentification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

Background

We tested whether genetic factors distinctly contribute to either development of coronary atherosclerosis or, specifically, to myocardial infarction in existing coronary atherosclerosis.

Methods

We did two genome-wide association studies (GWAS) with coronary angiographic ph...
S-EPMC3297116 | biostudies-literature
Sort   by:  
 Page size