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Background Breast cancer is the leading cause of cancer related deaths in women. Triple negative breast cancers are highly aggressive, have an overall poor prognosis and has limited therapeutic options. Previously, we have identified an environmental induced gene mdig that predicted the overall surv...
ORGANISM(S): Homo sapiens (Human) 
2020-12-10 | PXD016688 | Pride
Gene expression profile of WT and mdig/mina53 KO MDA-MB 231 breast cancer cells [RNA-Seq]
Histone methylation profiles of H3K4me3, H3K27me3, H3K9me3, and H3R8me2a in WT and mdig/mina53 KO BEAS-2B cells
The mineral dust-induced gene (mdig) is overexpressed in a number of human cancers, suggesting critical roles of this gene played on the pathogenesis of cancers. Unlike several other JmjC-domain containing proteins that exhibit histone demethylase activity, it remains enigmatic whether mdig is invol...
ORGANISM(S): Homo sapiens 
2020-02-15 | GSE145354 | GEO
The mineral dust-induced gene (mdig, also called as MINA or RIOX2) is upregulated in breast cancer and predicts poor overall survival of breast cancer patients. Our studies suggested the anti-metastasis feature of mdig in regulating the cell motility of breast cancer cells. Here we studied the trans...
ORGANISM(S): Homo sapiens 
2026-01-20 | GSE282125 | GEO
The mineral dust-induced gene (mdig, also called as MINA or RIOX2) is upregulated in breast cancer and predicts poor overall survival of breast cancer patients. Our studies suggested the anti-metastasis feature of mdig in regulating the cell motility of breast cancer cells. Here we studied the trans...
ORGANISM(S): Homo sapiens 
2026-01-20 | GSE282126 | GEO
Gene expression profile at single cell level of WT and mdig/mina53 KO MDA-MB 231 breast cancer cells
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