Me2 - OmicsDI

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Transcriptomics (3762)
Genomics (401)
Unknown (314)
Proteomics (136)
Multiomics (106)
Models (12)
Other (11)
Metabolomics (5)
Methylation profiling (2)

Organisms

Homo sapiens (1755)
Mus musculus (1029)
Rattus norvegicus (158)
Arabidopsis thaliana (132)
Saccharomyces cerevisiae (112)
Drosophila melanogaster (72)
Thermus thermophilus HB8 (71)
Danio rerio (63)
Salmo salar (36)
Caenorhabditis elegans (33)
Gallus gallus (29)
Escherichia coli (22)
Bos taurus (21)
Apis mellifera (20)
Candida albicans (19)
Schizosaccharomyces pombe (19)
Sus scrofa (18)
Daphnia magna (16)
Staphylococcus aureus (14)
Legionella pneumophila (13)
Mycobacterium tuberculosis (12)
Plasmodium falciparum (12)
Solanum tuberosum (11)
Oncorhynchus nerka (10)
Mycobacterium tuberculosis H37Rv (10)
Triticum aestivum (10)
Pseudomonas putida (9)
Fagus sylvatica (9)
Oncorhynchus mykiss (9)
Haemophilus influenzae 22.1-21 (1)

Organisms

Homo sapiens (26)
Mus musculus (11)
Caenorhabditis elegans (8)
Schizosaccharomyces pombe (3)
Arabidopsis thaliana (3)
Saccharomyces cerevisiae (2)
Drosophila melanogaster (2)
Bacillus anthracis str. Sterne (1)
Fundulus heteroclitus (1)
Eriobotrya japonica (1)
Saccharomyces cerevisiae BY4741 (1)
Oryza sativa Japonica Group (1)

Repository

biostudies-arrayexpress (4042)
LINCS (120)
MassIVE (69)
ENA (67)
geo (46)
jPOST (42)
EGA (34)
pride (15)
BioModels (12)
iProX (7)
GPMDB (4)
MetaboLights (4)

Tissue

Embryonic stem cell (3)
Permanent cell line cell (3)
Cell culture (2)
Epithelial cell (2)
Gastric adenocarcinoma cell (2)
T cell (2)
Brain (1)
Cell suspension culture (1)
Culture condition:CD8+ cell (1)
Embryo (1)
Fibroblast (1)
HeLa cell (1)
Stomach (1)

Disease

Normal (17)
Breast cancer (6)
Adenocarcinoma (4)
Neuroblastoma (4)
Glioblastoma multiforme (3)
Breast adenocarcinoma (2)
Rheumatoid arthritis (2)
Colon cancer (2)
Carcinoma (2)
Wilms tumour (2)
Blast crisis (1)
Neuroendocrine tumor (1)
Multiple sclerosis (1)
Prostate carcinoma lymph node metastasis (1)
Oropharynx squamous-cell carcinoma in DiseaseLocation oropharynx has DiseaseStaging lymph node negative (N0) (1)
T. circumcincta infection (1)
Specific-pathogen free (SPF) (1)
Not applicable (1)
Embryonic lethal at day 8.5 to 9.5 (1)
Colorectal cancer recurrence-free (1)
Allergic airways disease (1)
Squamous cell carcinoma has accession C0007137 in DiseaseStateDatabase NCI_Thesaurus (1)
Hutchinson Gilford Progeria Syndrome (1)
Non-metastatic melanoma (1)
Portal hypertension (1)
Insulin resistance (1)
Glioma (1)
Pancreatic ductal adenocarcinoma (1)
Limited cutaneous subset (1)
Infected (1)

Technology Type

Fluorescence intensity (113)
KINOMEscan (109)
Mass Spectrometry (15)
Shotgun proteomics (6)
Fluorescence imaging (4)
QPCR (3)
Mass spectrometry assay (3)
Gel-based experiment (3)
MEMA (2)
Affinity purification coupled with mass spectrometry proteomics (2)
Data-independent acquisition (2)
SRM/MRM (2)
Illumina MiSeq, HiSeq X Ten, NextSeq 500, Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500 (1)
Chromatography, Mass spectrometry (1)
DNA sequencing (1)
Mass spectrometry (1)
PCR (1)
RNA-seq (1)
Mass spectrometry (1)
Bottom-up proteomics (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
MSE (1)

Instrument Platform

NextSeq 500 (76)
Illumina NovaSeq 6000 (70)
Illumina HiSeq 2500 (65)
Illumina HiSeq 4000 (50)
Illumina HiSeq 2000 (32)
Axon GenePix 4000B scanning hardware (20)
Illumina MiSeq (17)
BGISEQ-500 (14)
Illumina HiSeq 1500 (14)
NextSeq 2000 (9)
G2565AA DNA microarray scanner [Agilent] (8)
Axon- GenePix4000B (8)
Scanning hardware (8)
Illumina Genome Analyzer IIx (7)
ScanArray 5000 [PerkinElmer] (6)
DNBSEQ-G400 (6)
NextSeq 550 (6)
GenePix Professional 4200A [Axon Instruments] (5)
GenePix 4000A [Axon Instruments] (5)
Other (3)
DNA Microarray Scanner BA [Agilent Technologies] (3)
GenePix 4000B [Axon Instruments] (3)
Illumina Genome Analyzer II (3)
DNBSEQ-T7 (3)
BD Influx sorter (2)
Agilent Bravo NGS workstation, Microlab STAR automated liquid handler (Hamilton Robotics), PCR machine (MJ Research Peltier Thermal Cycler) (2)
G2565BA DNA microarray scanner (2)
Agilent High resolution C scanner (2)
ScanArray scanning hardware (2)
G2500A GeneArray scanner [Agilent Technologies] (2)

Publication Date

2010 (499)
2015 (462)
2013 (459)
2014 (452)
2012 (426)
2011 (379)
2016 (311)
2008 (225)
2009 (200)
2023 (127)
2007 (104)
2022 (91)
2005 (89)
2021 (85)
2017 (71)
2020 (70)
2018 (67)
2006 (59)
2019 (50)
2024 (45)
2025 (37)
2026 (17)
2004 (15)
2003 (9)

UNIPROT ID/AC

Q01813 (2)
P43490 (2)
P17858 (2)
P21439 (2)
P05062 (2)
P09972 (2)
P04075 (2)
P07738 (2)
P00338 (2)
P07195 (2)
P14618 (2)
P04406 (2)
P30613 (2)
P06744 (2)
P06733 (2)
P09104 (2)
P13929 (2)
P08237 (2)
O14556 (2)
P00558 (2)
P07205 (2)
P18669 (2)
P60174 (2)
A0A1S3MBI7 (1)
A0A1S3RDV7 (1)
A0A1S3SLA8 (1)
B5X3P0 (1)
A0A1S3N3T3 (1)
A0A1S3NZZ4 (1)
A0A1S3P094 (1)

CHEBI ID

CHEBI:7916 (11)
CHEBI:67119 (11)
CHEBI:57692 (11)
CHEBI:37565 (11)
CHEBI:7125 (11)
CHEBI:37737 (11)
CHEBI:15905 (11)
CHEBI:17154 (11)
CHEBI:15999 (11)
CHEBI:32398 (11)
CHEBI:15539 (11)
CHEBI:30831 (11)
CHEBI:16264 (11)
CHEBI:18319 (11)
CHEBI:1989 (11)
CHEBI:30751 (11)
CHEBI:48854 (11)
CHEBI:371 (11)
CHEBI:18191 (11)
CHEBI:17025 (11)
CHEBI:16742 (11)
CHEBI:15366 (11)
CHEBI:30915 (11)
CHEBI:28938 (11)
CHEBI:17544 (11)
CHEBI:48153 (11)
CHEBI:15741 (11)
CHEBI:9532 (11)
CHEBI:18012 (11)
CHEBI:30744 (11)

Metabolite Name

(4-(2-((3- methylphenoxy)ace tyl)carbohydrazono yl)phenoxy)acetic acid (1)
2-[[3-(4-Methoxyphenoxy)-4-oxo-4H-chromen-7-yl]oxy]acetic acid (1)
N'-[(Z)-(2,3-dihydroxyphenyl)methylidene]naphthalene-2-sulfonohydrazide (1)
3-methoxy-2-[2-(2,4,7-trimethyl-1H-indol-3-yl)acetamido]propanoic acid (1)
1-(6-methoxy-3-methyl-1-benzofuran-2-carbonyl)piperazine-2-carboxylic acid (1)
2-(6-(2,5-Dimethoxyphenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid (1)
1,3-dioxo-2-(quinolin-8-yl)-2,3-dihydro-1H-isoindole-5-carboxylic acid (1)
1,4-diamino-9,10-dioxo-9,10-dihydro-2-anthracenesulfonic acid (1)
2,5-dimethyl-furan-3-carboxylic acid (3-ethoxy-4-hydroxy-benzylidene)-hydrazide (1)
2-(4-methyl-6-oxo-7,8,9,10-tetrahydro-6h-benzo(c)chromen-3-yloxy)-propionic acid (1)
6-methoxy-alpha-(2-methoxy-5-nitrophenylimino)-o-cresol (1)
[2-(methylthio)phenyl](3-oxopiperazin-1-yl)acetic acid (1)
2-(1-oxo-4-phenylphthalazin-2-yl)acetic acid�� (1)
4-Hydroxysulfamerazine (1)
1-(2-hydroxy-1-propyl)-3-phenylurea (1)
1,3,6,8-tetrahydroxy-2,7-naphthyridine (1)
1-Methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid (1)
Thieno[2,3-b]pyrazine-6-carboxylic acid (1)
FA 18:4+1O (1)
Adenosine 5'-diphosphate (1)
Beta-muricholic acid (1)
Tauro-omega-muricholic acid (1)
7-keto-lithocholic acid (1)
Murideoxycholic acid (1)
Chenodeoxycholic acid 24-acyl-beta-d-glucuronide (1)
Norcholic acid (1)
3beta-cholic acid (1)
Omega-murichoclic acid (1)
3beta-ursodeoxycholic acid (1)
Alpha-muricholic acid (1)

First Public Date

2019 (11)
2020 (9)
2023 (8)
2014 (8)
2018 (6)
2025 (5)
2026 (4)
2017 (4)
2024 (3)
2021 (3)
2015 (3)
2022 (1)
2016 (1)
2013 (1)

Modelling Approach

Constraint-based model (11)
Metabolic network (1)

Lab affiliation

Department of biology, Stanford University, The Gozani Lab (2)
Associate Professor, Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, USA (1)
Centre for Epigenetics and Department of Biochemistry and Molecular Biology, University of Southern Denmark Campusvej 55 DK-5230 Odense M, Denmark (1)
Department of Health Sciences and Technology (D-HEST) Institute Neurosciences, ETH Zurich (1)
EDyP (1)
Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania (1)
European Institute of Oncology (1)
Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, Laboratory of Pharmaceutical Biotechnology, Ghent University, Belgium (1)
Proteomics Facility, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands (1)
Proteomics center, Erasmus MC (1)
School of Biotechnology and Biomolecular Sciences, University of New South Wales, NSW, Australia (1)
School of Lifesciences, Tsinghua University, Beijing,China (1)
School of Lifesciences, Tsinghua Univesity, Beijing, China (1)
Unidade de Espectrometria de Massas e Proteômica (UEMP) Programa de Biologia Estrutural Bloco D, Primeiro andar, Sala 45 – Centro de ciências da saúde - Universidade Federal do Rio de Janeiro (1)

IsPrivate

False (12)

Submitter Keywords

FROG (3)
Not Peer Reviewed (1)

Classification

bacteria (1)

Modification

N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (2769)
RNA-seq of coding RNA (460)
ChIP-seq (239)
RNA-seq of non coding RNA (64)
ChIP-chip by tiling array (56)
Unknown experiment type (50)
Methylation profiling by array (49)
Other (40)
RNA-seq of coding RNA from single cells (37)
Comparative genomic hybridization by array (28)
Cell line - High-throughput sequencing (27)
MicroRNA profiling by array (27)
ChIP-chip by array (24)
DNA-seq (23)
Transcription profiling by tiling array (19)
Methylation profiling by high throughput sequencing (14)
ATAC-seq (13)
Animal - High-throughput sequencing (11)
Animal - One-color microarray (10)
RNA-seq of total RNA (10)
High-throughput sequencing (7)
RNAi profiling by array (6)
Cell line - One-color microarray (5)
Proteomic profiling by array (5)
Transcription profiling by SAGE (3)
Human - One-color microarray (3)
Genotyping by array (3)
Cell line - Single-cell sequencing (2)
Differential (2)
Human - High-throughput sequencing (2)

Release Date

2010 (506)
2013 (468)
2014 (455)
2012 (435)
2015 (408)
2011 (385)
2016 (283)
2008 (229)
2009 (206)
2023 (114)
2021 (110)
2022 (106)
2007 (104)
2005 (92)
2020 (79)
2018 (72)
2019 (61)
2006 (60)
2017 (56)
2024 (47)
2025 (33)
2004 (15)
2026 (10)
2003 (10)
2002 (2)
2001 (1)
1997 (1)

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Histone H3K4me3 Demethylase RBP2 Transcriptionally Activates PPARγ to Drive Lipid Metabolic Reprogramming in Gastric Carcinoma

This work investigates epigenetic driven lipid metabolic reprogramming in gastric carcinoma. We characterize that histone H3K4me3 demethylase RBP2 transcriptionally activates PPARgama by binding to its promoter region,thereby promoting lipogenic gene expression and intracellular lipid accumulatio...

2026-08-14 | MTBLS15324 | MetaboLights

Phospho-mimics-ME2-affinity-purified mass spectrometry analysis

This project aims to identify ME2 interaction proteins.

ORGANISM(S): Homo sapiens (Human)

2023-11-26 | PXD040377 | Pride

ChIP-seq of H3K4me1, me2 and me3 on mouse salivary gland cancer cells cultured in either adherent or non-adherent conditions

Investigating how the Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer. We performed mRNA-seq and ChIP-seq of H3K4me1, me2 and me3 on mouse salivary gland cancer cells that are kept in two different growth conditions, adherent culture and non-adherent sphere culture. Mouse...

ORGANISM(S): Mus musculus

2018-12-24 | E-MTAB-7514 | biostudies-arrayexpress

ME2 Promotes Proneural-Mesenchymal Transition and Lipogenesis in Glioblastoma.

Not available

S-EPMC8351415 | biostudies-literature

SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration.

Not available

S-EPMC10781994 | biostudies-literature

PRMT1-mediated methylation of ME2 promotes hepatocellular carcinoma growth by inhibiting ubiquitination.

Not available

S-EPMC11555414 | biostudies-literature

Genome-wide localization of Swi6 and H3-Lys9-me2 in wt and mutant starins of S. pombe

PRJNA816078 | ENA

ACAT1-Mediated ME2 Acetylation Drives Chemoresistance in Ovarian Cancer by Linking Glutaminolysis to Lactate Production.

Not available

S-EPMC11984883 | biostudies-literature

Genome-wide localization of Swi6 and H3-Lys9-me2 in wt and mutant starins of S. pombe

ChIP-on-ChIP experiments were performed to quantitate the genome-wide localization of heterochromatin proteins Swi6 and H3-Lys9-me2 in wild type versus polalpha mutant swi7H4, Pol delta mutant, dts2 and cut4 mutant cut4-993. Our results indicate that the localization of Swi6 and H3-Lys7-me2 at heter...

ORGANISM(S): Schizosaccharomyces pombe

2023-03-05 | GSE198590 | GEO

Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells.

Not available

S-EPMC3153071 | biostudies-literature

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4768 Results

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