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FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias in Lympho-myeloid Multipotent Progenitors WT multipotent progenitors were compared with FLT3-ITD multipotent progenitors
ORGANISM(S): Mus musculus 
Haematopoietic stem cells can differentiate into all blood cell types. In this process, cells become progressively restricted to a single cell type. The order in which differentiating cells loose lineage potential, and the prospective isolation of cells with a defined potential remains a long-standi...
ORGANISM(S): Mus musculus 
Gene expression of HSC (Lin-Sca-Kit+Flt3-) hematopoietic stem cells from Dicer D/+ mice was compared with LT-HSC from DicerD/D mice. BM cells were noncompetitively transplanted into irradiant recipients, and deletion induced by poly(IC) injection. Donor-derived HSCs were isolated by FACS sorting ...
ORGANISM(S): Mus musculus 
Background: Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by “bulk” assays and to uncover rare cell types. In human hematopoiesis, megakaryocytes and erythroid cells differentiate from a shar...
ORGANISM(S): Homo sapiens 
Illumina Human610 Quad arrays were used to genotype breast cell lines.
ORGANISM(S): Homo sapiens 
Not available
ORGANISM(S): Homo sapiens 
We performed RNA-sequencing of normal haematopoietic stem cells and progenitor populations and of Leukemic Stem Cells in CD34- Acute Myeloid Leukaemia.
ORGANISM(S): Homo sapiens 
Gene profiling of LSKCD150+CD48-CD34- hemetopoietic stem cells expressing (Vwf+) or not expressing a Vwf-EGFP BAC transgene
ORGANISM(S): Mus musculus 
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