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MetabolomicsSingle-Cell and Spatial Multi-Omics Reveal Mechanical Stress Driving Heterogeneous Xylem Development in Populus [Spatial metabolomics_MALDI imaging]
Xylem, the predominant tissue for structural support, forms tension wood with G-layer-rich fibers under mechanical stress. Despite being recognized over a century ago, three key biological questions remained unclear: (1) Are fibers in normal and tension wood distinct cells due to morphological diffe...
2025-06-16 | MTBLS12601 | MetaboLights
MetabolomicsSingle-Cell and Spatial Multi-Omics Reveal Mechanical Stress Driving Heterogeneous Xylem Development in Populus [Spatial metabolomics_LCM]
Xylem, the predominant tissue for structural support, forms tension wood with G-layer-rich fibers under mechanical stress. Despite being recognized over a century ago, three key biological questions remained unclear: (1) Are fibers in normal and tension wood distinct cells due to morphological diffe...
2025-06-16 | MTBLS12561 | MetaboLights
TranscriptomicsStress-Responsive MicroRNAs in Populus
MicroRNAs (miRNAs), a group of small non-coding RNAs, have recently become a subject of intense study. They are a class of post-transcriptional, negative regulators playing vital roles in plant development and growth. However, little is known about their regulatory roles in tree’s responses to the...
ORGANISM(S): Populus trichocarpa 
2010-05-26 | E-GEOD-10582 | biostudies-arrayexpress
ProteomicsWhole worm proteomics after optogenetically induced mechanical muscle stress (OptIMMuS)
This project includes 16 samples of transgenic C. elegans whole worm lysate after mechanical stress in 4 replicates of 4 conditions. Transgenic C. elegans strains expressing the optogenetic channelrhodopsin mutant ChR2(C128S;H134R)-FLAG in body wall muscle cells (PP3189 hhIs251[myo-3p::ChR2(C128S,H1...
ORGANISM(S): Caenorhabditis elegans 
2024-07-16 | PXD045078 | Pride
C. elegans Optogenetics Mechanical stress Muscle 
ProteomicsMulti-omics analyses reveal the mechanical-stress-dependent changes in trabecular meshwork cytoskeletal-extracellular matrix interactions
Trabecular meshwork (TM) tissue is subjected to constant mechanical stress due to the ocular pulse created by the cardiac cycle. This induces alterations in membrane lipids and associated cell-cell adhesion and cell-extracellular matrix (ECM) interactions triggering intracellular signaling responses...
ORGANISM(S): Homo sapiens (Human) 
2022-08-30 | PXD031347 | Pride
Cyclic mechanical stretch Human trabecular meshwork Global proteomic analysis (lc-ms/ms) Mrna sequencing. Lipidomic analysis 
TranscriptomicsTranscription profiling of lung samples from mouse and rat treated with mechanical ventilation
This series contain mouse and rat lung samples treated with mechanical ventilation and corresponded controls.
ORGANISM(S): Mus musculus 
2007-07-20 | E-GEOD-2368 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of dog lung samples after mechanical ventilation
This series contain unilateral mechanical ventilated canine lung samples.
ORGANISM(S): Canis familiaris 
2008-06-11 | E-GEOD-1935 | biostudies-arrayexpress
GenomicsTranscriptional response to mechanical wounding stress in Oryza sativa
Transcriptional response to mechanical wounding stress in Oryza sativa
PRJNA1174730 | ENA
TranscriptomicsTranscription profiling of mouse tendon, cornea, and skin fibroblasts stimulated with mechanical stress to test the hypothesis that fibroblasts from different tissues are phenotypically distinct from one another.
In order to test the hypothesis that fibroblasts from different tissues are phenotypically distinct from one another, we have subjected tendon, skin and corneal fibroblasts of fetal mouse to mechanical stimulation by fluid flow and analyzed the transcriptional responses of the cells using Affymetrix...
ORGANISM(S): Mus musculus 
2007-10-12 | E-GEOD-3486 | biostudies-arrayexpress
GenomicsRNA-sequencing of mechanical stress induced osteoarthritis-like damage in aged human cartilage explants treated with the anti-deiodinase iopanoic acid
The current study aimed to confirm chondroprotective effects of the D2 inhibitor iopanoic acid (IOP) in an ex vivo aged human osteochondral explant model in which injurious mechanical stress is applied to inflict OA-like damage. This dataset contains RNA-seq (Illumina HiSeq X ten) of osteochondral e...
EGAS00001006242 | EGA
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