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TranscriptomicsMEDIATOR subunit med8 binding in Saccharomyces cerevisiae
The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. Genome wide localization studies have demonstrated that Mediator occupancy not only correlates with high levels of transcription, but that the complex also is present at transc...
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-22 | E-GEOD-28613 | biostudies-arrayexpress
GenomicsArabidopsis MED8 functions in oxidative stress
Arabidopsis MED8 functions in oxidative stress
PRJNA593852 | ENA
TranscriptomicsTranscription profiling of MED8 N-truncation mutant, MED18 deletion mutant and MED20 deletion mutant yeast
expression profiles of MED8 N-truncation mutant, MED18 deletion mutant and MED20 deletion mutant against a wild type reference.
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-09 | E-MEXP-1175 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast Med2, Med3, Med18, Med20 deletion mutants and with a C-terminal truncation of Med8
We made deletions of Med2, Med3, Med18, Med20 and a C-terminal truncation of Med8. We expression profiled the mutants against a common reference.
ORGANISM(S): Saccharomyces cerevisiae 
2008-03-08 | E-MEXP-1341 | biostudies-arrayexpress
ProteomicsThe Arabidopsis Mediator complex subunit 8 regulates oxidative stress responses
Hydrogen peroxide (H2O2) signals regulate plant growth and defense by orchestrating genome-wide transcriptional re-programming, however, the specific mechanisms that regulate H2O2-dependent gene expression are poorly understood. Here we report the identification of the Mediator complex subunit MED8 ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-09-17 | PXD016615 | Pride
Arabidopsis Mediator complex Catalase Oxidative stress Med8 Hydrogen peroxide 
GenomicsEffect of knockdown of MED8 on gene expression in bladder carcinoma cell T24.
Effect of knockdown of MED8 on gene expression in bladder carcinoma cell T24.
PRJNA1281607 | ENA
TranscriptomicsArabidopsis MED8 functions in oxidative stress
In this work, we describe a TDNA insertion mutant for Mediator complex subunit 8 (MED8) that regulates the oxidative stress responses. Wild-type Col-0 and med8 seedlings were growth under control condition or oxidative stress (induced by methyl viologen treatment) and were subjected to RNA-seq profi...
ORGANISM(S): Arabidopsis thaliana 
2021-03-14 | GSE141547 | GEO
TranscriptomicsEffect of knockdown of MED8 on gene expression in bladder carcinoma cell T24.
To explore the function of MED8 in the regulation of gene expression in bladder cancer, we established MED8-knockdown T24 cells. We then conduct gene expression profiling analysis using data obtained from RNA-seq of MED8-knockdown cells and control cells.
ORGANISM(S): Homo sapiens 
2026-02-11 | GSE300652 | GEO
UnknownTargeting MED8 enhances sorafenib sensitivity in hepatocellular carcinoma by disrupting epithelial-mesenchymal transition mechanisms.
Not available
S-EPMC12541920 | biostudies-literature
UnknownMED8 is related to tumor immunity and has predictive value in the prognosis and treatment of glioma.
Not available
S-EPMC12304387 | biostudies-literature
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