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TranscriptomicsTranscription profiling of control and catalase-deficient Arabidopsis (Arabidopsis thaliana) plants
In plants, reactive oxygen species and, more particularly, hydrogen peroxide (H2O2) play a dual role as toxic by-products of normal cell metabolism and as regulatory molecules in stress perception and signal transduction. Peroxisomal catalases are an important sink for photorespiratory H2O2. Using A...
ORGANISM(S): Arabidopsis thaliana 
2005-10-11 | E-MEXP-449 | biostudies-arrayexpress
ProteomicsAnalysis of cysteine redox state with age in flies overexpressing catalase
Dysregulation of redox homeostasis has been implicated in the ageing process and the pathology of age-related diseases. To study redox signalling by hydrogen peroxide in vivo, we upregulated levels of the enzyme catalase in Drosophila.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-06-30 | PXD060330 | Pride
Drosophila Catalase Ageing 
TranscriptomicsGenes Express in Catalase Overexpression MAECs
Study the global genes expression in mouse aorta endothelial cells (MAECs) overexpressing human catalase (hcatTg). The wild type and overexpressing human catalase (hcatTg) MAECs grown to 80% confluence in six-well plates were made quiescent in serum-free DMEM for 12 h and then cultured in 10% FBS DM...
ORGANISM(S): Mus musculus 
2011-03-08 | E-GEOD-27701 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of Arabidopsis Col-0 and catalase 2 mutant define interactions between CO2, daylength and H2O2
Growth daylength, ambient CO2 level, and intracellular hydrogen peroxide (H2O2) availability all impact plant function by modulating signalling pathways, but interactions between them remain unclear. Using a whole-genome transcriptomics approach, we exploited the conditional photorespiratory nature ...
ORGANISM(S): Arabidopsis thaliana 
2012-03-07 | E-GEOD-27985 | biostudies-arrayexpress
ProteomicsCATALASE INTERACTING RCC1-LIKE 1 contributes to hydrogen peroxide homeostasis in Arabidopsis
Reactive oxygen species (ROS) are central regulators of plant growth and stress responses, and their cellular levels are tightly controlled by antioxidant systems, including the evolutionarily conserved catalases that decompose hydrogen peroxide (H2O2) predominantly within peroxisomes and glyoxysome...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-07-15 | PXD073328 | Pride
H2o2 homeostasis Plant growth Arabidopsis thaliana Stress-response Rcc1-like protein 
ProteomicsOverexpression of catalase delays age-related cardiac disease by preventing oxidative cysteine modifications
Reactive protein cysteine thiolates are instrumental in redox regulation. Aging associated to oxidative stress, can impair redox signaling by damaging essential cysteine thiolates. Our initial study found that cardiac-specific overexpression of catalase, can protect from oxidative stress and delay c...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-24 | PXD002479 | Pride
Metabolism Proteomics Reversible cysteine thiol oxidation Tmt Post-translational protein modifications Mass spectrometry Cardiac aging and disease 
ModelsChance1952_Catalase_Mechanism
This model is described in the article: The mechanism of catalase action. II. Electric analog computer studies. Britton Chance, David S Greenstein, Joseph Higgins, CC Yang, Arch Biochem. 1952 37:322-39. PubmedID:14953444 Summary: An electric analog computer has been constru...
2024-09-02 | BIOMD0000000282 | BioModels
ProteomicsIntradermal Delivery of Catalase via Extracellular Vesicles for Targeted Photoaging Therapy
We engineered a 313-cell line to produce EVs that were subsequently loaded with catalase (CAT), a key antioxidant enzyme. These CAT-loaded EVs (313EVs) exhibited high loading efficiency and maintained both vesicle integrity and enzymatic activity
ORGANISM(S): Rattus Norvegicus 
2025-12-12 | PXD072392 |
TranscriptomicsPhotorespiratory stress in catalase deficient plants
Hydrogen peroxide (H2O2) can act as a signaling molecule that influences various aspects of plant growth and development, including stress signaling and cell death. To unravel the molecular mechanisms that regulate the response towards an impact of increased H2O2 levels in plant cells, we focused on...
ORGANISM(S): Arabidopsis thaliana 
2016-06-10 | E-GEOD-77171 | biostudies-arrayexpress
TranscriptomicsGenes Express in Catalase Overexpression MAECs
Study the global genes expression in mouse aorta endothelial cells (MAECs) overexpressing human catalase (hcatTg).
ORGANISM(S): Mus musculus 
2011-03-08 | GSE27701 | GEO
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