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TranscriptomicsDIFFERENTIAL GENE EXPRESSION OF MEDULLARY THYROID CARCINOMA REVEALS SPECIFIC MARKERS ASSOCIATED WITH GENETIC CONDITIONS.
Transcriptional analysis of 49 primary medullary thyroid carcinoma tumors. Comparisons MTCM918T vs MTC634 and MTCM918T vs MTCWT. 49 (52 hybridized tumors with 3 replicates) primary Medullary Thyroid Carcinoma (MTC) cases were hybridized onto a cDNA microarray in order to identify the unique markers ...
ORGANISM(S): Homo sapiens 
2013-11-26 | E-GEOD-32662 | biostudies-arrayexpress
GenomicsWhole Genome and Transcriptome Analysis of Medullary Thyroid Cancer - samples
Sequence data from two medullary thyroid carcinoma patients: WGS datasets generated from tumors and matched normal tissues and RNA-Seq from tumors are included.
EGAD00001001618 | EGA
ProteomicsQuantitative proteomics analysis of medullary thyroid carcinoma
Medullary thyroid cancer (MTC) accounts for less than 5% of all thyroid cancers, and it is a rare neuroendocrine tumor which derives from calcitonin-secreting thyroid C cells.Given the underlying mechanism involved in MTC remain unclear, the development and the specific pathways of MTC require furth...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD005898 | Pride
Proteomics Syt1 Medullary thyroid carcinoma Ecm remolding 
GenomicsWhole genome and transcriptome analysis of medullary thyroid cancer
Medullary thyroid cancer is the neoplasm of the calcitonin-producing parafollicular cells of the thyroid gland. The hormone calcitonin acts to lower the blood calcium level, counteracting the effects of the parathyroid hormone; it can also serve as a biomarker for the presence or recurrence of medul...
EGAS00001001473 | EGA
TranscriptomicsComprehensive Transcriptome Profiling of Sporadic Medullary Thyroid Carcinoma
In this study, we performed the transcriptome analysis of a cohort comprising 72 (20 already published E-MTAB-11599) MTC (medullary thyroid carcinoma) specimens from patients with different genetic background (w/o RET or RAS mutations).
ORGANISM(S): Homo sapiens 
2026-01-07 | E-MTAB-15198 | biostudies-arrayexpress
ProteomicsMulti-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma
Medullary thyroid carcinoma (MTC) is a rare and aggressive neuroendocrine tumor. Our study involves 482 retrospective MTC formalin-fixed, paraffin-embedded (FFPE) samples from 452 patients, collected from 10 Chinese clinical centers. Quantification of 10,092 proteins were achieved via diaPASEF, and ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-13 | PXD063677 | Pride
TranscriptomicsGenome Haploidisation with Chromosome 7 Retention in Oncocytic Follicular Thyroid Carcinoma
Recurrent non-medullary thyroid carcinoma (NMTC) is a rare disease. We initially characterized 27 recurrent NMTC: 13 papillary thyroid cancers (PTC), 10 oncocytic follicular carcinomas (FTC-OV), and 4 non-oncocytic follicular carcinomas (FTC). A validation cohort composed of benign and malignant (bo...
ORGANISM(S): Homo sapiens 
2012-08-29 | E-GEOD-31828 | biostudies-arrayexpress
UnknownRevised American Thyroid Association guidelines for the management of medullary thyroid carcinoma.
Not available
S-EPMC4490627 | biostudies-literature
TranscriptomicsHuman thyroid adenomas, carcinomas, and normals
Human samples of various thyroid carcinomas, adenomas, and normals, each from a different patient, had mRNA assays performed using Affymetrix HG_U133A arrays, with 22283 probe-sets. The 99 samples consisted of 4 normals, 10 follicular adenomas, 13 follicular carcinomas, 7 oncocytic adenomas, 8 onco...
ORGANISM(S): Homo sapiens 
2011-02-09 | E-GEOD-27155 | biostudies-arrayexpress
no omics definedTranscription profiling of human medullary thyroid carcinoma cell line TT sunitinib or vehicle treatment time course
The aim of the study was to identify major gene expression changes associated to sunitinib response in a human medullary thyroid carcinoma (MTC)ﾠmodel.ﾠWe developed an in vitro kinetic microarray study. The humanﾠﾠMTC cell line, the TT cells, were treated with 250 nM sunitinib or vehicle during 1, 3...
ORGANISM(S): Homo sapiens 
2011-02-26 | E-TABM-929 | biostudies-arrayexpress
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