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ProteomicsSurvey of megadalton protein assemblies from Dictyostelium discoideum
The analysis of high-abundance megadalton protein complexes in Dictyostelium discoideum cell lysates was conducted as follows: the solubilized protein fraction was subjected to size-exclusion chromatography isolating fractions corresponding to the megadalton region, followed by ion-exchange chromato...
ORGANISM(S): Dictyostelium Discoideum Ax2 (ncbitaxon:366501) 
2025-02-25 | MSV000097213 | MassIVE
ProteomicsCytoplasmic lattices are megadalton storage complexes for tubulin and ubiquitination factors in mammalian oocytes 
Mammalian oocytes store proteins for embryonic development on abundant structures known as cytoplasmic lattices (CPLs); however, the mechanisms by which they achieve this are unclear, largely because the molecular composition of the lattices themselves is unknown. Here, we use cryo-electron microsco...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-11 | PXD073451 | Pride
Maternal storage Cryo-electron microscopy Tubulin Cytoplasmic lattices Ubiquitination factors 
UnknownPeptide Assembly Directed and Quantified Using Megadalton DNA Nanostructures.
Not available
S-EPMC6764022 | biostudies-literature
UnknownMegadalton-node assembly by binding of Skb1 to the membrane anchor Slf1.
Not available
S-EPMC4148255 | biostudies-literature
UnknownA Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies.
Not available
S-EPMC7297045 | biostudies-literature
UnknownMegadalton complexes in the chloroplast stroma of Arabidopsis thaliana characterized by size exclusion chromatography, mass spectrometry, and hierarchical clustering.
Not available
S-EPMC2938090 | biostudies-literature
ProteomicsIdentification of high molecular weight protein/protein complexes in human cultured cells (HEK293T) LC-MS/MS
Phosphoribosyl pyrophosphate synthetase (PRPS) is a highly conserved enzyme that conducts the chokepoint reaction of nucleotide biosynthesis by converting ribose-5-phosphate (R-5-P) to phosphoribosyl pyrophosphate (PRPP). Due to the presence of multiple isoforms and related PRPS-associated proteins ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD059156 | Pride
Prps complex High molecular weight proteins Protein complexes Megadalton assemblies Lc-ms/ms 
UnknownATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Not available
S-EPMC7785744 | biostudies-literature
UnknownCombining Surface-Induced Dissociation and Charge Detection Mass Spectrometry to Reveal the Native Topology of Heterogeneous Protein Complexes.
Not available
S-EPMC10874503 | biostudies-literature
UnknownEvolutionary Refinement of DNA Nanostructures Using Coarse-Grained Molecular Dynamics Simulations.
Not available
S-EPMC7613751 | biostudies-literature
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