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TranscriptomicsIntegrated genomic and transcriptional profiling yields putative marker genes for cervical cancer
A better understanding of the consequences of recurrent (epi)genetic alterations that occur during cervical carcinogenesis is essential in the search for novel biomarkers. In this study we determined genome-wide expression profiles of 10 squamous cell carcinomas (SCCs), 5 adenocarcinomas (AdCAs) and...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-6473 | biostudies-arrayexpress
TranscriptomicsGastric cancers of Western European and African patients
Gastric cancer is the second most common cause of cancer death worldwide, but incidence and mortality rates show large variations across different countries. Variation in risk factors between different populations, including environmental and host factors influencing gastric cancer risk, have been r...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-GEOD-22789 | biostudies-arrayexpress
TranscriptomicsSmall bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers
Purpose: Small bowel adenocarcinoma (SBA) is a rare cancer and consequently the number of clinical trials has been very limited due to the small numbers of patients. Chemotherapy regimens are currently rather arbitrarily chosen between either a colorectal (CRC) or a gastric cancer (GC) regimen. Chr...
ORGANISM(S): Homo sapiens 
2011-06-13 | E-GEOD-23418 | biostudies-arrayexpress
TranscriptomicsIdentification of markers associated with deregulated hTERT during HPV-medaited transformation
Although high-risk human papillomavirus (HPV) infection plays a major role in the development of cervical cancer, additive oncogenic events are involved as well. One key event involves increased activity of telomerase resulting from a deregulated expression of its catalytic subunit hTERT. Our previo...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-8288 | biostudies-arrayexpress
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